The Innate Immune System Flashcards
1
Q
Name some PAMPS in gram -ve bacteria.
A
LPS
Lipopeptides/proteins
Porins
2
Q
Name some gram +ve bacteria PAMPs.
A
Peptidoglycan
Lipoteichoic acid
3
Q
Name some mycobacterial PAMPs.
A
Lipoarabinomannan
Mannose-rich glycans
4
Q
Name a general bacterial PAMP.
What PRR is this detected by?
A
Flagellin
TLR5
5
Q
Give 6 examples of opsonins.
A
C3b C4b
IgG IgM
CRp and MBL
6
Q
Which complement proteins form membran attack complex?
A
C5-C9
7
Q
Name the 3 complement pathways.
A
Classical - Antigen-AB complex
Alternative - Cell surface constituents
MBL - MBL binds to mannose containing residues of proteins found on many microbes.
