the final countdown Flashcards
Vit _ overuse: nausea, vomiting, vertigo, blurred vision, alopecia, HSM, hyperlipidemia, dry skin, papilledema
Vit A toxicity
testes lymph drains to
para aortic nodes
scrotum lymph drains to
superficial inguinal nodes
effect of tamoxifen on endometrium
hyperplasia and possible cancer
symmetrical proximal muscle weakness, difficulty climbing stairs/carrying heavy objects, anti-Jo-1 autoantibodies, endomysial mononuclear infiltrate and patchy necrosis
polymyositis (assoc with interstitial lung disease and myocarditis)
what is anti Jo-1 autoantibody
in polymyositis–histidyl tRNA synthetase
nucleolus is the primary site of _RNA transcription
ribosomal RNA (RNA pol I)
confabulation and permanent memory loss
Korsakoff syndrome (Wernicke symptoms–oculomotor dysfunction, ataxia, confusion– resolve with thiamine)
MC cardiovascular manifestation assoc with SLE
pericarditis–relieved by sitting forward
cuboidal granulosa cells in a rosette pattern with coffee bean nuclei
Call-Exner bodies
elevated acetylcholinestease in amniotic fluid
failed fusion–neural tube defects
end stage renal disease with bleeding
uremic platelet dysfunction. platelet count normal but bleeding time increased
MOA ethosuximide
blocks T type Ca channels that trigger and sustain discharges in thalami neurons
phenytoin, carbamazepine, valproic acid MOA
decreases Na current in cortical neurons
MCC death in patients with diabetes mellitus
coronary heart disease