Thalamus Flashcards
The epithalamus consists of which two nuclei?
The pineal and habenular nuclei
The pineal gland releases…?
melatonin
The habenular nuclei serves what purpose?
Limbic relay nuclei–emotional state and memories. Receives input via the stria medullaris of the thalamus.
What kind of cells are pinealocytes?
modified photoreceptors that are responsible for regulating our circadian rhythm
How is the pineal gland innervated?
Through sympathetic pathways
What are the components of the subthalamus?
Subthalamic nucleus and zona incerta
What causes hemibalism?
Damage to subthalamic nucleus
What exactly is the thalamus?
Collection of nuclei in the lateral third ventricle
Are there many excitatory or inhibitory neurons in the thalamus?
Inhibitory. GABAergic
What are the two modes that thalamic neurons exist in?
Either in burst or tonic mode
What is burst mode?
Thalamic neurons with rhythmic firing which inhibits thalamic neurons
What is tonic mode?
Thalamic neurons in a state where they are responding to input and conveying information. High burst of action potentials
What are the two types of thalamic nuclei? What is each responsible for?
Specific relay nuclei vs association nuclei.
Specific relay nuclei filter sensory information and provide feedback from the cortex
Association nuclei are involved with complex functions like attention, memory and eye movement
What are the intralaminar nuclei involved in?
Ascending reticular activating system and connections between the basal ganglia and limbic system
Which nucleus of the thalamus is the only one that does not send its major output to the cortex?
Reticular thalamic nucleus–an inhibitory feedback nucleus
How does the thalamus affect the cerebral cortex?
Relaying sensation or motor feedback and filtering that input
Also, to maintain normal levels of cortical activity by modulating input
What state are burst cells in? (think polarization)
They are hyperpolarized. With slight depolarization by Ca++ channels, they fire an action potential but then are inactivated for a longer period of time to prevent the rapid firing that is seen in tonic mode