Tests of coagulation Flashcards

1
Q

What is the normal PTT

A

25-32 seconds

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2
Q

what is the normal aPTT

A

12-14 seconds

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3
Q

What is the target INR for a patient in Warfarin

A

2-3 times control

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4
Q

What is the normal platelet count

A

150,000-300,000

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5
Q

__________ monitors platelet function but is rarely used in clinical practice

A

Bleeding time

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6
Q

Normal ACT is _________. It should exceed _______ before going to CPB

A

90-120 seconds

400 seconds

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7
Q

Factors must be reduced by more than _______ before a change in aPTT is observed.

A

30%

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8
Q

aPTT measures the time it take to form a clot using______, ____________ and __________.

A

phospholipid
calcium
an activator

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9
Q

Normal aPTT is?

A

25-32 seconds

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10
Q

What does the normal length of aPTT and PT tell you about the speed of the 2 coagulation pathways

A

Normal aPTT is longer than normal PT because the intrinsic pathway is slower than the extrinsic pathway.

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11
Q

PT measures the time it takes to form a clot using ___________ and ____________

A

Tissue factor and calcium

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12
Q

Factors must be reduced by more than ______ before a change in PT is observed?

A

30%

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13
Q

Normal INR in healthy patients is ________

A

Approximately 1

It compares patient’s PT to the standard mean PT

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14
Q

ACT should be measured ______ minutes after heparin and _______ minutes thereafter.

A

3 minutes and every 30 minutes thereafter

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15
Q

In large heparin doses, _______ is more accurate than PTT.

A

ACT

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16
Q

_________ plt count increases surgical bleeding

A

< 50,000

17
Q

_________ plt count increases spontaneous bleeding risk

A

<20,000

18
Q

Normal bleeding time is________

A

2-10 minutes

19
Q

______ and________ prolong bleeding time

A

Aspirin and NSAIDs

20
Q

_____________ evaluates the ability to form a plt plug

A

Bleeding time

21
Q

_________ monitors for fibrinolysis

A

D-Dimer

22
Q

Elevated D-Dimer indicates?

A

Presence of a thrombus somewhere in the body.