T2 DM treatment Pathway Flashcards by Katie Saunders | Brainscape

Q

HbA1c >48 on lifestyle interventions

A

Standard release metformin

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Q

1st intensification: HbA1c rises to 58

A

Metformin +

DPP-4i
pioglitazone
SU
SGLT-2

Aim HbA1c 53

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Q

2nd intensification: HbA1c rises to 58

A

Metformin +
- DDP-4i + SU
- pioglitazone + SU
Insulin

HbA1c 53

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Q

Metformin CI or not tolerated

A

Try modified release metformin
DDP-4i, pioglitazone or SU

HbA1c 48 (53 for SU)

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Q

1st intensification: HbA1c rises to 58, metformin CI

A

DPP-4i + pioglitazone
DPP-4i + SU
Pioglitazone + SU

HbA1c 53

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Q

2nd intensification: HbA1c rises to 58, metformin CI

A

Insulin based treatment

HbA1c 53

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