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BBDA 5 > Sulfa, Trimethoprin, Quinolones > Flashcards

Sulfa, Trimethoprin, Quinolones Flashcards

1
Q

Sulfonamides Spectrum

A

Gram +: Strep , Staph (MRSA) Listeria

Gram -: Entero

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2
Q

Sulfonamides PK

A

Good CNS-P
High protein binding
Renal

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3
Q

Sulfonamide ADRs

A

GI
Photosensitivity
Hypersensitivity

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4
Q

Trimethoprim Spectrum

A

Similar to Sulfonamides

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5
Q

Trimethoprim ADRs

A

Increased SCr

Hyperkalemia

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6
Q

Trimethoprim + Sulfamethoxazole

A

Synergistic effect

Dosing based on TMP not SMX

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7
Q

1st Gen Quinolone spectrum

A

Gram - only

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8
Q

2nd Gen Quinolone spectrum

A

Gram - only
Ciprofloxacin covers pseudomonas
Atypicals

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9
Q

3rd Gen Quinolone spectrum

A

Gram +: Strep
Gram -: Enterobacteriaceae
Levofloxacin covers pseudomonas

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10
Q

Quinolone PK

A

Inhibited by Ca, Fe, Mg, Al, take 2 hours apart
No CNS-P
Renal except Moxifloxacin

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11
Q

Quinolone ADRS

A 
GI
CNS
Photosensitivity
Peripheral Neuropathy
QT prolongation
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BBDA 5 (6 decks)

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