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APhA 10th > Sterile Productions (Ch5) > Flashcards

Sterile Productions (Ch5) Flashcards

1
Q

What is the limit of volume that can be given IM in upper arm? (APhA 10th)

A

2 mL

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2
Q

What is the limit of volume that can be given IM in buttocks? (APhA 10th)

A

5 mL

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3
Q

What is the limit of volume that can be given SubQ? (APhA 10th)

A

2 mL

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4
Q

What is the limit of volume that can be given by intradermal route? (APhA 10th)

A

0.1 mL

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5
Q

What consideration needs to be made regarding preservatives in intrathecal administration? (APhA 10th)

A

No preservatives in drugs

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6
Q

What needle gauge is the smallest? (APhA 10th)

A

27 gauge

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7
Q

What needle gauge is the largest? (APhA 10th)

A

13 gauge

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8
Q

What is ampule filtering? (APhA 10th)

A

Any solution must be filtered with a 5-micron filter needle or filter straw because glass particles fall into the ampule when broken

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9
Q

What is the general beyond-use date for entered multidose vials? (APhA 10th)

A

28 days

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10
Q

In parenteral nutrition, should calcium or phosphate be added first? (APhA 10th)

A
  1. Phosphate

2. If calcium is added first there is an increased risk of precipitate formation

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11
Q

What is the compatibility of heparin and aminoglycosides? (APhA 10th)

A
  1. A precipitate forms

2. This is a ionic interaction. Heparin = (anionic) Aminoglycosides = (cationic)

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12
Q

What is oxidation? (APhA 10th)

A

An electron loss that cause a positive increase in valence

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13
Q

What is reduction? (APhA 10th)

A

An electron is gained causing a decrease in valence

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14
Q

Name 3 drugs that are sensitive to light? (APhA 10th)

A
  1. Amphotericin B
  2. Furosemide
  3. Sodium Nitroprusside
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15
Q

What color is sodium nitroprusside when deteriorated by light? (APhA 10th)

A
  1. It has a faint brownish color when in D5W

2. Light causes a blue color by the reduction of the ferric to ferrous ion

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16
Q

A nurse wants to administer 2 amps of sodium bicarbonate through an IV already giving dopamine HCl 800 mg in 500 mL D5W. Is this appropriate? (APhA 10th)

A
  1. The pH of dopamine is 3-4.5 and NaHCO3 = 8.
  2. A color change occurs due to decomposition
  3. The pH of NaHCO3 is too high for dopamine stability

APhA 10th (3 decks)

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