Small Bowel Cancer Flashcards
RF
Hereditary Cancer Syndromes - Adenocarcinoma Chronic Inflammation - Adenocarcinoma - Crohn’s - Lymphoma - Celiac Diet - Alcohol, refined sugar, red meat, smoked food Tobacco
Clinical
- Asymptomatic
- Abdominal Pain
- Weight Loss
- Nausea and Vomiting
- Gastrointestinal Bleeding
- Intestinal Obstruction
Small Bowel cancer tumors
I. Adenocarcinoma
II. Carcinoid
III. Lymphoma
IV. Sarcoma
MC cancer of small bowel
adenocarcinoma
MC site of adenocarcinoma
duodenum
Adenocarcinoma mainly due to
crohn’s disesae
Carcinoid tumors commonly found
ileum
Clinical carcinoid syndrome
Watery diarrhea, flushing, sweating, wheezing, dyspnea, abdominal pain, hypotension
Cause carcinoid syndrome
Precipitated by: alcohol blue cheese chocolate red wine or exercise anesthesia
Dx carcinoid syndrome
Urinary excretion of 5-HIAA
Serum Chromagranin A
Somatostatin receptor scintigraphy
Tx carcinoid syndrome
Octreotide
Avoidance of Triggers
Tx carcinoid tumors
Surgical Excision
+/- chemotherapy
Chemoembolization
sarcoma found where
jejunum and ileum
Most common tumor in sarcoma
gastrointestinal stroma
What is the MC extranodal form of lymphoma
Non-hodgkins and Marginal Zone B cell lymphoma
Predisposing conditions of lymphoma
Autoimmune Disease
Immunodeficiency Syndromes (e.g HIV)
Long-Standing Immunosuppressive therapy
Crohn’s Disease
Imaging Small bowel cancer
Upper Gastrointestinal series/small bowel follow through
Enteroclysis (CT, MRI or conventional)
CT scan with IV and oral contrast
Direct visualization of small bowel cancer
Upper endoscopy
Push enterescopy
Double-balloon enteroscopy
Wireless Video Capsule
Pre-op screening of small bowel cancer
CBC
LFTS
PET SCAN/CT
Tx adenocarcinoma
surgical
Tx carcinoid
surgical
Tx sarcoma
Surgical Excision + Imatinib (advanced disease)
Tx lymphoma
Surgical Excision (Node negative) + Chemotherapy (Node positive)
