Slide 10

Question 1

Example of polyploidy

Answer 1

Down syndrome (trisomy 21)

Question 2

Can polyploidy cause new species to appear

Answer 2

Yes

Question 3

SPARCL is an example of _____

Answer 3

Gene duplication event

Question 4

Pericentric vs paracentric inversion

Answer 4

Pericentric inversion includes centromere

Paracentric inversion does not include centromere

Paracentric for this reason should be safer

Question 5

Whole genome shotgun approach vs next generation sequencing

Answer 5

Rapid DNA sequencing by randomly fragmenting the genome, assembling overlapping sequences to reconstruct the entire genome.

Next generation: more advanced and efficient iteration, enabling faster and cheaper sequencing of entire genomes or specific regions

Question 6

Genomes vary in

Answer 6

Size
Number of genes
Genome desntiy

Question 7

Describe the relationship between genome size and number of protein coding genes

Answer 7

Proportional

Question 8

Define transposable elements

Answer 8

Stretches of DNA that can move from one location to another within the genome (75% in humans)

Question 9

Does gene number explain complexity?

Answer 9

No! Humans only have 50% more genes than drosophila melanogaster

Question 10

Why is alternative splicing useful?

Answer 10

Allows one gene to code multiple proteins