Seronegative seropositive arthritis

Question 1

features of seronegative disease

Answer 1

• oligoarticular
• asymmetric
• distribution

Question 2

features of peripheral SpA

Answer 2

• whole digit
• asymmetric
• ## lower extremity

Question 3

2 unique features of spondyloarthritis

Answer 3

• enthesites

dactylitis

Question 4

features of pathology of RA

Answer 4

• neutrophils infiltrate
• extensive angiogenesis
• synovial membrane proliferation

Question 5

common joint affected by SpA

Answer 5

discovertebral joint - syndesmophyte

Question 6

Clinical features of SLE

Answer 6

• malar rash
• oral ulcers
• LUNG infiltrates
• photosensitivity

Question 7

Clinical features of scleroderma

Answer 7

• raynaud’s
• telangectasias
• sclerodactyly
• interstitial lung disease
  esophageal dysmotility

Question 8

Clinical features of inflammatory myositis

Answer 8

• if dermato- skin labial folds included
• MCP/PIP
• CK! and EMG

Question 9

Clinical features of GCA

Answer 9

• large vessel vasculitis

- constitutional symptoms

Question 10

presenting symptoms of GCA

Answer 10

constitutional
headache
jaw claudication
scalp tenderness
shoulder/pelvic girdle pain!!!

Question 11

Diagnose SLE

Answer 11

• CBC, Creatinine, urinalysis
• autoantibodies, ANA, dsDNA, anti-sm, low levels of C3 C4
• kidney biopsy

Question 12

Vasculitis extra articular manifestations

Answer 12

• epistaxis - otitis
• lung
• purpura
• kidney
• stroke
  MI

Question 13

Diagnose vasculitis

Answer 13

• blood work
• tissue biopsy
• imaging (dilataions/changes in vessels)

Question 14

GCA coexists with

Answer 14

polymyalgia rheumatica