Selected Toxins & Their Antidotes Flashcards

1
Q

Acetaminophen

A

NAC

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2
Q

Anticholinergic agents

A

Physostigmine

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3
Q

Benzodiazepines

A

Flumazenil

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4
Q

Black widow spider envenomation

A

Antivenin Latrodectus mactans

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5
Q

Carbon monoxide

A

Oxygen

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6
Q

Coral snake envenomation

(Eastern US or Texas coral snake)

A

Antivenin Micrurus fulvius

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7
Q

Cyanide

A
  • Cyanide antidote kit
    • Amyl nitrite + sodium nitrite + sodium thiosulfate
  • Hydroxocobalamin (Vitamin B12)
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8
Q

Digitalis glycosides

A

Digoxin-specific Fab antibodies

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9
Q

Heavy metals

(mercury, manganese, copper, gold, nickel, zinc, lead, arsenic)

A
  • D-penicillamin
    • lead, mercury, arsenic, copper
  • Dimercaprol (British anti-lewisite in oil)
    • heavy metals, lewisite (chemical weapon)
  • DMSA
    • lead, mercury, arsenic, other metals
  • EDTA, calcium
    • lead, nickel, zinc, manganese
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10
Q

Inducers of dystonia

A

Diphenhydramine

Benztropine

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11
Q

Inducers of methemoglobinemia

A

Methylene blue

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12
Q

Iron

A

Deferoxamine

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13
Q

Isoniazid

A

Pyridoxine (Vitamin B6)

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14
Q

Methanol, ethylene glycol

A

Ethanol, fomepizole

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15
Q

Narcotics

A

Naloxone

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16
Q

Organophosphates, carbamate pesticides

A

Atropine

Pralidoxime (2-PAM for organophosphates)

17
Q

Pit viper snake bite

(rattlesnake, water moccasin, copperhead envenomation)

A

Antivenin, Crotalidae polyvalent

Crotalidae polyvalent Fab antibodies

18
Q

ß-blockers, Ca channel blockers

A

Glucagon

19
Q

Sulfonylurea oral hypoglycemic agents

A

Octreotide

Glucagon