Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Anesthesia Pharmacology > Sedatives & Antiseizure > Flashcards

Sedatives & Antiseizure Flashcards

1
Q

PROPOFOL (DIPRIVAN)
MECHANISM OF ACTION:

A

Enhances and directly activates GABA Receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

PROPOFOL (DIPRIVAN)
ADULT DOSING:
Induction

A

2 mg/kg

(1-2.5 mg/kg)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

PROPOFOL (DIPRIVAN)
ADULT DOSING:
GA Infusion

A

200 mcg/kg/min

(100-300 mcg/kg/min)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

PROPOFOL (DIPRIVAN)
ADULT DOSING:
Sedation Infusion

A

50 mcg/kg/min

(25-100 mcg/kg/min)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

PROPOFOL (DIPRIVAN)
ADULT DOSING:
PONV

A

15 mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

PROPOFOL (DIPRIVAN)
KIDS DOSING:
Induction

A

3 mg/kg

(2.5-3.5 mg/kg)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

PROPOFOL (DIPRIVAN)
KIDS DOSING:
GA Infusion

A

250 mcg/kg/min

(150-350 mcg/kg/min)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

PROPOFOL (DIPRIVAN)
KIDS DOSING:
Sedation Infusion

A

100 mcg/kg/min

(80-150 mcg/kg/min)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

PROPOFOL (DIPRIVAN)
CONCENTRATION:

A

10 mg/mL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

PROPOFOL (DIPRIVAN)
ONSET

A

30 seconds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

PROPOFOL (DIPRIVAN)
DURATION

A

5 minutes

(5-10 minutes)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

PROPOFOL (DIPRIVAN)
ELIMINATION

A

Liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

PROPOFOL (DIPRIVAN)
PRIMARY EFFECTS:

A

Sleep
Vasodilation
Cardiac Depression
Blunts SNS response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

PROPOFOL (DIPRIVAN)
COMPLICATIONS:

A

Hypotension
Respiratory Depression
Lose Airway Reflexes
Histamine release

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

PROPOFOL (DIPRIVAN)
CONTRAINDICATIONS

A

Allergy to Propofol
Egg allergy (but not really)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

PROPOFOL (DIPRIVAN)
MISCELLANEOUS:

A

Discard within 6 hours of being drawn up

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Ketamine (Ketalar)
MECHANISM OF ACTION:

A

NMDA Receptor Antagonist (Blocks Glutamate) with some Opioid Receptor activation
Blocks the Thalamus, essentially disconnecting the cerebral cortex from the brainstem
Blocks the perception of pain and activates Opioid Receptors
Increases the RELEASE of norepinephrine
Direct cardiac depressant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Ketamine (Ketalar)
ADULT DOSING:
Induction IV

A

1 mg/kg

(1-2 mg/kg)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Ketamine (Ketalar)
ADULT DOSING:
Induction IM

A

5 mg/kg

(5-10 mg/kg)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Ketamine (Ketalar)
ADULT DOSING:
Analgesia IV

A

10-50 mg
0.5 mg/kg

(0.2 - 1 mg/kg) (don’t exceed 1 mg/kg in a 30 minute period)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Ketamine (Ketalar)
KIDS DOSING:
Induction IV

A

2 mg/kg

(1-3 mg/kg)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Ketamine (Ketalar)
KIDS DOSING:
Induction IM

A

5 mg/kg

(5-10 mg/kg)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Ketamine (Ketalar)
KIDS DOSING:
Analgesia IV

A

0.1 mg/kg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Ketamine (Ketalar)
CONCENTRATION:

A

10 mg/mL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Ketamine (Ketalar) ONSET: IV
30 seconds (30-60 seconds)
26
Ketamine (Ketalar) DURATION:
20 minutes (10-30 minutes)
27
Ketamine (Ketalar) ELIMINATION:
Liver Kidneys (Active metabolite)
28
Ketamine (Ketalar) PRIMARY EFFECTS:
“Dissociative Anesthesia” Analgesia Increased BP & HR Bronchodilation
29
Ketamine (Ketalar) COMPLICATIONS:
Hypertension Tachycardia Increased Secretions - Increased Laryngospasm Risk PONV Hallucinations Increased Intracranial Pressure Increased Intraocular Pressure Seizures Histamine release
30
Ketamine (Ketalar) CONTRAINDICATIONS:
Porphyria Hypertension Increased ICP Procedures of Pharynx, Larynx, Bronchial Tree History of CVA Psych disorder Convulsive disorder
31
Ketamine (Ketalar) MISCELLANEOUS:
Pretreat with Glycopyrrolate (Robinul) - Secretions Pretreat with Versed! - Hallucinations & Delirium
32
Etomidate (Amidate) MECHANISM OF ACTION:
Enhances GABA binding
33
Etomidate (Amidate) ADULT DOSING: IV
0.3 mg/kg (0.2-0.6 mg/kg)
34
Etomidate (Amidate) KIDS DOSING:
Not for kids under 10 years old Kids over 10 is the same as adults (0.2-0.4 mg/kg)
35
Etomidate (Amidate) CONCENTRATION:
2 mg/mL
36
Etomidate (Amidate) ONSET:
30 seconds
37
Etomidate (Amidate) DURATION:
5 minutes (3-10 minutes)
38
Etomidate (Amidate) ELIMINATION:
Liver Plasma Esterases
39
Etomidate (Amidate) PRIMARY EFFECTS:
Sedation Anticonvulsant Decreased ICP Minimal Cardiovascular Effects
40
Etomidate (Amidate) COMPLICATIONS:
Respiratory Depression (small tidal volumes) PONV Adrenal Suppression (for 6 hours) Myoclonus Pain on injection
41
Etomidate (Amidate) CONTRAINDICATIONS:
Porphyria Immunosuppressed patients
42
Etomidate (Amidate) MISCELLANEOUS:
No Histamine release
43
DEXMEDETOMIDINE (PRECEDEX) MECHANISM OF ACTION:
Central Alpha 2 Agonist Activates presynaptic Alpha 2 Receptors in the CNS, blocking the release of Norepinephrine
44
DEXMEDETOMIDINE (PRECEDEX) ADULT DOSING: Bolus
4 mcg (4-12 mcg)
45
DEXMEDETOMIDINE (PRECEDEX) ADULT DOSING: Loading before infusion
0.5 mcg/kg over 10 minutes (0.5 - 1 mcg/kg over 10 minutes)
46
DEXMEDETOMIDINE (PRECEDEX) ADULT DOSING: Infusion
0.5 mcg/kg/hour (0.2 - 1 mcg/kg/hr)
47
DEXMEDETOMIDINE (PRECEDEX) KIDS DOSING: Loading before infusion
Same as adults 0.5 mcg/kg over 10 minutes
48
DEXMEDETOMIDINE (PRECEDEX) KIDS DOSING: Infusion
Same as adults 0.5 mcg/kg/hour (0.2 - 1 mcg/kg/hr)
49
DEXMEDETOMIDINE (PRECEDEX) CONCENTRATION:
4 mcg/mL
50
DEXMEDETOMIDINE (PRECEDEX) ONSET:
5 minutes
51
DEXMEDETOMIDINE (PRECEDEX) DURATION:
1 hour (1-2 hours)
52
DEXMEDETOMIDINE (PRECEDEX) ELIMINATION:
Liver
53
DEXMEDETOMIDINE (PRECEDEX) PRIMARY EFFECTS:
Sedation Anxiolysis Analgesia Antisialagogue
54
DEXMEDETOMIDINE (PRECEDEX) COMPLICATIONS:
Bradycardia Heart Block Hypotension Dry mouth Hypertension with IV bolus
55
DEXMEDETOMIDINE (PRECEDEX) CONTRAINDICATIONS:
Bradycardia Hypotension
56
DEXMEDETOMIDINE (PRECEDEX) MISCELLANEOUS:
No Respiratory Depression
57
Midazolam (Versed) MECHANISM OF ACTION:
Benzodiazepine - Enhances GABA Receptor Binding
58
Midazolam (Versed) ADULT DOSING: PreOp Anxiolysis
2 mg (1-5 mg) (0.2-0.4 mg/kg)
59
Midazolam (Versed) ADULT DOSING: Induction
0.2 mg/kg (0.2-0.4 mg/kg)
60
Midazolam (Versed) KIDS DOSING: Oral PreOp
0.5 mg/kg 30 minutes before induction
61
Midazolam (Versed) KIDS DOSING: IV
0.05 mg/kg
62
Midazolam (Versed) CONCENTRATION:
1 mg/mL
63
Midazolam (Versed) ONSET: IV
1 minute (1-2 minutes)
64
Midazolam (Versed) ONSET: Oral
30 minutes
65
Midazolam (Versed) DURATION:
2 hours (2-6 hours)
66
Midazolam (Versed) ELIMINATION:
Liver
67
Midazolam (Versed) PRIMARY EFFECTS
Anxiolysis Amnesia Sedation Antiemetic
68
Midazolam (Versed) COMPLICATIONS
Respiratory Depression
69
Midazolam (Versed) CONTRAINDICATIONS:
Old People (over 70)
70

Anesthesia Pharmacology (20 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions