Secondary Immune Deficiencies Flashcards
1
Q
AIDS-defining illnesses:
A
- Esophageal candidiasis
- Deep fungal infections
- HSV (that lasts longer than 1 month)
- Kaposi’s sarcoma
- Lymphoma
2
Q
Affects thymus, lymph node, and spleen development
A
Malnutrition
3
Q
Affects the dividing cells in bone marrow (RBCs and WBCs)
A
Chemotherapeutic Agents
4
Q
Used to inhibit WBC response and can decrease inflammation in a specific site
A
Corticosteroids
5
Q
Suppresses humoral response
A
Corticosteroids
6
Q
In diabetic patients, especially those with ketoacidosis, we see:
A
deep fungal infections
such as mucormycosis (Zygomycosis)
7
Q
Immunodeficiencies secondary to HIV:
A
- Lymphopenia = decrease in T cells
- Decreased & Altered T-cell function
- Altered monocyte/macrophage function
- Polyclonal B-cell activation