Schizophrenia Flashcards
Diagnosis
process of organising symptoms into categories based on which symptoms cluster together
Reliability
consistent diagnosis based on symptoms over time and culture
Validity
extent to which SZ is a unique syndrome with characteristics, signs and symptoms. Diagnosis matches symptoms
Diagnostic manuals
ICD 10 – 2 negative symptoms
DSM 5 – 1 positive symptom
Symptoms of SZ
Positive – delusions, hallucinations
Negative – speech poverty, avolition
Diagnosis and classification - evaluation
comorbidity
gender bias
symptom overlap
cultural bias
Genetics
uses twins and family studies to investigate. 108 candidate genes, many assoicatrd with excess dopamine. Gottesman – MZ have 48% risk; DZ have 27%
Dopamine hypothesis
dopamine is an excitatory neurotransmitter which, in abnormal amounts, leads to SZ symptoms.
Hypodopaminergia and Hyperdopaminergia
Hypodopaminergia – in the cortical region, too little dopamine can lead to avolition
Hyperdopaminergia – in the subcortical region, too much dopamine can lead to speech poverty and delusions
Neural correlates
patterns of structure or activity that occur in conjunction with SZ
Ventral striatum – found to be associated with avolition
Superior temporal gyrus and anterior cingulate gyrus – associated with hallucinations. (lower activity levels)
Biological explanations - evaluation
Nature/nurture debate
problem of cause/effect
biological determinism
Schizophrenogenic mother
a mother who is cold and rejecting of affection. In this – creates an atmosphere of paranoia.
Expressed emotion
this is the amount of conflict in the house. If the level is high, it can lead to stress which causes relapse. EE is a family communication style that involves criticism, hostility and emotional over-involvement.
Bateson’s double bind theory
when a person receives mixed messages about what is right and what is wrong. For example parents who say they care whilst appearing critical.
Lack of development of internally coherent construction of reality. Leads to irrational thinking
Central control
the ability to suppress automatic responses when performing actions. Malfunction can explain disorganised speech and thoughts.