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Oral Histo Final > Salivary glands flash > Flashcards

Salivary glands flash Flashcards

1
Q

What is the function of mucins in the saliva?

A

Responsible for lubricating the mucosal surface (aid in swallowing) and providing a protective barrier. Also important for trapping bacteria and sugar providing for their clearance.

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2
Q

What is the function of bicarbonate in the saliva?

A

Buffering acids in the mouth

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3
Q

What is the function of Proline-rich proteins in the saliva?

A

Binds calcium allowing for super saturation which contributes to remineralization.

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4
Q

What is the function of statherin in the saliva?

A

Binds calcium allowing for super saturation which contributes to remineralization.

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5
Q

What molecules contribute to the antimicrobial functions of saliva?

A

Lysozyme, peroxidase, defensins, histatins, and IgA.

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6
Q

What is the function of growth factors in saliva?

A

Can aid in tissue repair (Epidermal growth factor and nerve growth factor)

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7
Q

What is the function of amylase in saliva?

A

Dissolve starch

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8
Q

What is the function of lipase in saliva?

A

Breaks down fats into free fatty acids and glycerol

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9
Q

What is the function of water in the saliva?

A

Dissolves stimuli for transport to taste receptors.

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10
Q

What is the normal daytime salivary flow rate?

A

.3-.4 ml/min

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11
Q

What is the normal daytime salivary volume?

A

.8-1.1 ml

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12
Q

What percentage saliva volume does the parotid gland contribute to the mouth?

A

60%

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13
Q

What percentage saliva volume does the submandibular gland contribute to the mouth?

A

25%

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14
Q

What percentage saliva volume does the sublingual gland contribute to the mouth?

A

7-8% each

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15
Q

What secretes lingual lipase? What does it do?

A

Von Ebner’s glands (breaks down triglycerides into free fatty acids)

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16
Q

The other minor salivary glands are the main source of what to the saliva?

A

Mucins

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17
Q

What duct is connected to the parotid gland?

A

Stenson’s duct

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18
Q

What duct is connected to the submandibular duct?

A

Whartons duct

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19
Q

What duct is connected to the sublingual gland?

A

Barholin’s and Rivinus’s duct

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20
Q

What does the work of a gland?

A

Parenchyma

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21
Q

What are the supporting structures of a gland?

A

Stroma

22
Q

What makes up the Parenchyma in salivary glands?

A

Epithelium

23
Q

What makes up the Stroma in salivary glands?

A

Connective tissue

24
Q

What is the outer stroma of the salivary gland?

A

The capsule

25
Q

What is the inner stroma of the salivary gland?

A

The septa

26
Q

What is the secretory portion of the parenchyma?

A

Acini

27
Q

What is the order of ducts from smallest to largest?

A

Intercalated, Striated (Secretory), Collecting (excretory).

28
Q

When do the parotid glands develop?

A

Week 6 IU

29
Q

When do the submandibular glands develop?

A

Week 6 IU

30
Q

When do the sublingual and minor salivary glands develop?

A

Weeks 8-12 IU

31
Q

From where does the parenchyma develop?

A

Ectoderm or endoderm

32
Q

From where does the stroma develop?

A

Neural Crest Cells

33
Q

What process is responible for salivary gland clefting?

A

Suppression/redirection of ecadherin expression

34
Q

What is another molecule critical to the clefting process?

A

Cleftin

35
Q

What induces cleftin?

A

Fibronectin

36
Q

What are the two actions of cleftin?

A

INHIBITION OF E-CADHERIN, upregulation of snail2

37
Q

What do acini cells secrete? What are their tonicity?

A

Water, ions, proteins. Isotonic

38
Q

What do duct cells secrete/resorb? What are their tonicity?

A

Resorb Na+ Cl-, secrete bicarb and proteins; hypertonic

39
Q

What controls salivary secretion?

A

Neural control (In contrast to many other glands controlled by blood-borne hormones)

40
Q

What is the path of parasympathetic innervation of salivary glands?

A

Brainstem - 7th and 9th cranial nerves - synapse on post ganglionic neurons near gland

41
Q

What is the path of sympathetic innervation of salivary glands?

A

Originate in Intermediolateral nucleus of spinal cord - synapse in the superior cervical ganglion - supply glands

42
Q

What is the sympathetic nervous system responsible for in salivary glands?

A

Protein secretion.

43
Q

What is the parasympathetic nervous system responsible for in salivary glands?

A

Fluid secretion

44
Q

What do serous acinar cells secrete? What do they not secrete?

A

Amylase, PRP’s. They do NOT secrete mucins in appreciable amounts

45
Q

What type of acinar cell has an oval nuclei pressed toward the base?

A

Mucous cell

46
Q

What do mucous cells secrete?

A

Mucins

47
Q

How are the secretory granules of serous and mucous secreting cells different?

A

In mucous cells secretory granules have mucins which are more pale staining than those of serous cells

48
Q

What is a myoepithelial cell?

A

Specialized epithelial cell with contractile properties.

49
Q

What type of duct is absent in minor salivary ducts?

A

Striated/secretory ducts

50
Q

Describe an intercalated duct cell

A

Cuboidal with a LARGE centrally placed nucleus

51
Q

What do striated duct cells do?

A

Reabsorb sodium and chloride forming a hypotonic solution (ATP dependent). Secrete bicarbonate

52
Q

How do striated duct differ from intercalated duct cells?

A

Striated duct cells have infoldings (striations) on their basal end and are much more elongated cells compared to the more round intercalated duct cells. Striated duct cells contain many mitochondria to power their ATP dependent resorption.

Oral Histo Final (3 decks)

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