SAAF Flashcards

1
Q

sindrome antifosfolipidos

A

trombofilia autoinmune adquirida impulsada por anticuerpos circulantes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

CLOTS

A

coagulacion defecto
livedo reticularis
obstetricos - aborto
trombocitopenia
SLE asociada lupus eritematoso ssitemica

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

LABS

A

PPT - prolongados
PTN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

asociado a

A

LES 30%
AR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

SAAF aumento de la coagulacion

A

abortos espontaneos y trmbosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

anticuerpos

A

anti cardiolipina

anti B2 glicoproteina 1

ac anticuagulante lupico

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

prueba rapida de reaginina plasmatica

A

deteccion no especifica para sifilis, detecta anticuerpos ANTICARDIOLIPINA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

triggers infección

A

VIH
malaria
VHC
Sifilis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

triggers medicamentos

A

procainamida
propanolol
hidrozalazina
quinidina

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

criterios

A

criterios 1 clinico y 1 laboratorio

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

mutacion en gen

A

HDLRA7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

criterio clinicos

A

Eventos trombosis
Complicaciones embarazo:
- 1 aborto espontaneo ><10 SDG / 2 AS <10SDG
- 1 nacido en >34 SDG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

criterios de laboratorio

A
  • anticardiolipina
  • anti B2 glicoproteina 1
  • anti coagulacion lupica
  • TTP prolongado

positivos en 2 ocasiones con 2 semanas de diferencia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

tratamiento

A

1º warfarina - siempre en todos los pacientes

2º HBPM / HNF = INR terapeutico 1-2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

prevenir trombosis T

A

aspirina y evitar FR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

embarazos despues de 6 semanas postparto

A

warfarina

17
Q

antes de parto tx

A

HBPM

18
Q

TV tx

A

warfarina / acenocumarina

19
Q

obstetrico

A

enoxaparina 400m c/d 12
ASS c/d 24 hrs

20
Q

edad promedio del diagnostico

A

45 años

21
Q

deteccion

A

TTPa y ensayo de veneno de vibora de Russel diluido

22
Q

anticuerpo mas frecuente que regula el complemento y la coagulacion (en forma de J)

A

anti b2 glicoproteina

23
Q

teoria del segundo golpe

A

1- eventos tromboticos ocasionales

***2- empuje homeostatico a favor de coagulacion (infeccions, enf asociadas, anticonceptivos - estrogenos)

24
Q

complicaciones obstetricas

A

perdidas gestacionales en el 1er trimestre, abortos espontaneos