S1B5 - Pharmacology Mneumonics Flashcards

1
Q

What drugs are associated with crystal-induced kidney injury?

A

Other drugs associated with crystal-induced kidney injury can be remembered be mnemonic SOMATIC

  • Sulfasalazine
  • Orlistat
  • Methotrexate
  • Acyclovir
  • Triamterene
  • Indinavir (and other protease inhibitors)
  • Ciprofloxacin
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2
Q

What are the four main processes of pharmakokinetics?

A

Pharmacokinetics:

  • ADME
    • Absorption
    • Distribution
    • Metabolism
    • Elimination
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3
Q

What are the major indications for interferon alpha therapy?

A

IFN-α (interferon-α) indications can be remembered by the mnemonic “CCHHARM

  • Chronic HBV & HCV infections
  • Condyloma acuminatum (HPV 6 and 11)
  • Hairy cell leukemia
  • HHV-8 - Kaposi sarcoma
  • Alpha-interferon
  • Renal cell carcinoma
  • Malignant melanoma
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4
Q

When you see a drug ending in -antadine, what should you think?

A

Amantadine and rimantadine

  • inhibit viral M2 proton channels.
  • Influenza virus treatment
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5
Q

When you see a drug ending in -mavir, what should you think?

A

Oseltamavir and Zanamavir

  • Neuraminidase inhibitors
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6
Q

When you see a drug ending in -clovir, what should you think?

A

Acyclovir, valacyclovir, famcyclovir, ganciclovir

  • Prodrugs
  • Activated by viral kinases (thimidine kinase)
  • Viral DNA polymerase inhibitors
  • Chain terminators
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