Rogers and Kesner⭐

Question 1

Year

Answer 1

2003

Question 2

Sample

Answer 2

30 rats

Question 2

Aim

Answer 2

Determine the role of acetylcholine in the formation of spatial memory.

Question 3

Procedure

Answer 3

Familiarized rats with maze by putting food in corners.

Hippocampus injected with scopolamine (antagonist) or saline (placebo).

10 minuted later, re-ran maze.

Encoding: D1: ttttt to D1: TTTTT
Retrieval: D2: ttttt to D1: TTTTT

Question 4

Results and conclusion

Answer 4

Took longer and made more mistakes learning maze overall.

Encoding: scopolamine made more mistake than placebo on D1: TTTTT

Retrieval: No difference in retrieval of memories already created.

Shows that acetylcholine plays an important role in the consolidation of spatial memories.