Revision lecture spleen Flashcards

1
Q

what does the red pulp do?

A

recycles red blood cells, metabolises haemoglobin

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2
Q

what does white pulp do?

A

antibody synthesis, removal of bacteria and blood cells coated with antibodies

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3
Q

describe the blood supply from the heart to the spleen

A

aorta, abdominal aorta, celiac artery, splenic artery

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4
Q

describe the veins from the spleen to the liver?

A

splenic vein to hepatic portal vein

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5
Q

whats the risk of hyposplenism?

A

sepsis

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6
Q

Two things that can cause hyposplenism?

A

sickle cell anaemia

splenectomy

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7
Q

test for hyposplenism?

A

the presence of Howell Jolly bodies in blood film

these are normally removed by the spleen

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8
Q

causes of splenomegaly and whY (3)

A

Haemolytic anaemia- Increased workload
Portal hypertension due to some liver damage- congestion and back pressure into the spleen
leukaemia/lymphomas infiltration- spleen is the location of many white blood cells

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9
Q

which three pathogens are asplenic patients most at risk from?

A

Streptococcus pneumoniae
Haemophilus Influenzae
Meningococcus

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