Respiratory drugs

Question 1

What does DLCO measure?

Answer 1

Measures the diffusion capacity of lungs to CO

Question 2

Name an example of a restrictive disease

Answer 2

Idiopathic pulmonary Fibrosis

Question 3

Cytokine in balance released in Asthma include?

Answer 3

TH2 —> IL4,5,9,13

Question 4

Name a parasympathetic innervation drug

Answer 4

Ipratropium Bromide

Question 5

Name a leukotrine receptor antagonist

Answer 5

Montelukast

Question 6

Name a monoclonal antibody drug

Answer 6

Omalizumab

Question 7

NANC releases what two things to cause dilation

Answer 7

NO + VIP

Question 8

Bronchial Asthma is an accumulation of what?

Answer 8

Eosinophils / lymphocytes

Question 9

Name the procedure which examines bronchial asthma

Answer 9

Bronchoalveolar lavage

Question 10

What are anticholinergics used for?

Answer 10

Muscarinic receptor antagonist that bind to AcH

Question 11

Name a Anticholinergic drug

Answer 11

Atropine

Question 12

Name a glucocorticoid steroid

Answer 12

Dexamethasone

Question 13

What does glucocorticoids suppress? What do they inhibit?

Answer 13

Suppress inflam. genes

Inhibit cytokine mediators

Question 14

Albuterol

Answer 14

Mimics Epinephrine

Question 15

Cromolyn sodium

Answer 15

Mast cell stabiliser

Question 16

G—>cAMP—>PKA—->……

Answer 16

Relaxation

Question 17

Xanthine

Answer 17

Theophylline

Inhibits cell activation

Question 18

Montelukast is what type of antagonist

What’s it combined with

Answer 18

CysLT1 antagonist

Inhaled corticosteroid

Question 19

Problems of Montelukast

Answer 19

Slow onset

Question 20

Why are asthma drugs safe to use for long time

Answer 20

Not addictive

Effectiveness isn’t reduced by use

Question 21

Who benefits from montelukast

Answer 21

Atopic patients

Moderate to severe asthma

Question 22

What does salmeterol increase in target cells?

Answer 22

cAMP