Respiratory Flashcards

1
Q

What do central chemoreceptors monitor?

A

Carbon dioxide levels in the cerebrospinal fluid.

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2
Q

Where are peripheral chemoreceptors located?

A

In the carotid arteries and aorta

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3
Q

How does CO₂ affect blood pH?

A

It lowers pH by forming carbonic acid.

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4
Q

What happens in acidosis?

A

Hypoventilation leads to reduced breathing and CO₂ buildup.

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5
Q

What happens in alkalosis

A

Hyperventilation causes rapid breathing and excessive CO₂ loss.

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6
Q

Diffusion

A

Movement of gases depends on their solubility and interaction with liquid

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7
Q

Normal respiratory rate baby and infants

A

30-60 30-40

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8
Q

What’s glycolysis

A

It is the first stage of cellular respiration, occurring in the cytoplasm, where glucose is broken into pyruvate without producing carbon dioxide.

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9
Q

What is the function of the medulla oblongata in respiration?

A

regulate the basic rhythm of breathing.

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10
Q

What is the role of the pons in respiration?

A

The pons modifies the rhythm of breathing by coordinating smooth transitions between inhalation and exhalation, but it does not control the basic rhythm itself.

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11
Q

What happens when carbon dioxide levels rise in the blood?

A

The brain signals to increase ventilation.

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12
Q

Why is carbon monoxide toxic?

A

It displaces oxygen from hemoglobin, reducing oxygen transport in the blood.

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13
Q

How do buffer systems maintain blood pH?

A

By converting strong acids or bases into weaker ones.

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14
Q

What does reduced arterial oxygen content indicate?

A

Decreased hemoglobin levels or saturation.

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15
Q

Why does oxygen diffuse into the arterial ends of pulmonary capillaries and carbon dioxide diffuse into the alveoli?

A

Because of differences in partial pressures.

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16
Q

Why does oxygen diffuse out of the arterial ends of tissue capillaries and carbon dioxide diffuse out of the tissue?

A

Because of differences in partial pressures.

17
Q

What happens in the lungs (alveoli and pulmonary capillaries)?

A

Oxygen diffuses into the blood from the alveoli.
• Carbon dioxide diffuses out of the blood into the alveoli due to differences in partial pressures.

18
Q

What happens in the tissues (tissue capillaries and cells)?

A

Oxygen diffuses out of the blood into the tissues.
• Carbon dioxide diffuses into the blood from the tissues, driven by partial pressure differences.

19
Q

What are the two main factors oxygen delivery to tissues depends on?

A
  1. Cardiac Output (CO)
    1. Arterial Oxygen Content (CaO₂)
20
Q

What is cardiac output (CO), and why is it important?

A

Cardiac output is the amount of blood the heart pumps per minute. A higher cardiac output means more oxygen-rich blood is delivered to tissues, which is essential for meeting the body’s oxygen demands.

21
Q

What is the formula for cardiac output?

A

Cardiac Output = Heart Rate (HR) × Stroke Volume (SV)

22
Q

How does heart rate (HR) affect cardiac output?

A

Heart rate refers to how many times the heart beats per minute. A higher heart rate increases cardiac output, improving oxygen delivery to tissues.

23
Q

How does stroke volume (SV) affect cardiac output?

A

Stroke volume is the amount of blood the heart pumps with each beat. An increase in stroke volume raises cardiac output, improving oxygen delivery.

24
Q

What happens if cardiac output is low?

A

If cardiac output is low, tissues may not receive enough oxygen to function properly, even if the blood contains enough oxygen.

25
Q

How does arterial oxygen content (CaO₂) influence oxygen delivery?

A

Arterial oxygen content is the amount of oxygen in the blood. Efficient oxygen binding by hemoglobin ensures that adequate oxygen is delivered to tissues.

26
Q

What does arterial oxygen content (CaO₂) depend on?

A
  1. Oxygen bound to hemoglobin in red blood cells.
    1. A small amount of oxygen dissolved in plasma.
27
Q

How does hemoglobin affect oxygen delivery?

A

Most oxygen (98.5%) is carried by hemoglobin as oxyhemoglobin. If hemoglobin levels are low (e.g., anemia) or binding is impaired (e.g., carbon monoxide poisoning), oxygen delivery decreases.

28
Q

What is the formula for oxygen delivery to tissues?

A

Oxygen Delivery = Cardiac Output × Arterial Oxygen Content