RENAL DISEASES PART 1 Flashcards

1
Q

immune-mediated

A

GLOMERULAR

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2
Q

infection/toxic substances

A

TUBULAR
INSTERSTITTIAL

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3
Q

GLOMERULAR

A
  1. Acute Tubular Necrosis
  2. Fanconi’s Syndrome
  3. Nephrogenic Diabetes Insipidus
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4
Q

TUBULAR

A
  1. Urinary Tract Infection
  2. Acute Interstitial Nephritis
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5
Q

INSTERSTITTIAL

A
  1. Renal Calculi/Lithiasis
  2. Renal Failure
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6
Q

majority are of immune origin

A

GLOMERULAR DISEASES

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7
Q

exposure to chemicals and toxins

A

GLOMERULAR DISEASES

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8
Q

disruption of the electrical membrane charges

A

GLOMERULAR DISEASES

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9
Q

deposition of amyloid material from systemic disorders

A

GLOMERULAR DISEASES

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10
Q

basement membrane thickening

A

GLOMERULAR DISEASES

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11
Q

refers to a sterile, inflammatory process that affects the granules and is associated with the finding of blood, protein, and casts in the urine

A

glomerulonephritis

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12
Q

deposition of immune complexes, formed in conjunction of Group A Streptococcus infection on the glomerular membranes

A
  1. Acute PostStreptococcal Glomerulonephritis
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13
Q

Glomerulonephritis presenting as nephritic syndrome

A
  1. Acute PostStreptococcal Glomerulonephritis
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14
Q

deposition of immune complexes from systemic immune disorders (ex. SLE) on the glomerular membrane

A
  1. Rapidly Progressive/Crescentic Glomerulonephritis
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15
Q

crescentic – cellular proliferation of epithelial cells inside the bowman’s which forms crescents

A
  1. Rapidly Progressive/Crescentic Glomerulonephritis
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16
Q

Deposition of antiglomerular basement membrane antibody to glomerular and alveolar basement

A
  1. Goodpasteur Syndrome
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17
Q

Intial pulmonary complaints (hemoptysis)

A
  1. Goodpasteur Syndrome
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18
Q

Development of hematuria
Morphological changes: resemble rapidly progressive (crescentic)

A
  1. Goodpasteur Syndrome
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19
Q

Causes a granuloma-producing imflammation of the small blood vessels of primarily the kidney and respiratory system

A
  1. Wegener’s Granulomatosis
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20
Q

Dx: (+) Antineutrophilic cytoplasmic antibody (ANCA)

A
  1. Wegener’s Granulomatosis
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21
Q

Occurs only in children following viral respiratory infections

A
  1. Henoch Schonlein Purpura
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22
Q

Allergic purpura that causes decrease in the number of platelets and affects vascular integrity

A
  1. Henoch Schonlein Purpura
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23
Q

A pronounced thickening of the glomerular basement membrane resulting from the deposition of IgG immune complexes

A
  1. Membranous Glomerulonephritis
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24
Q

Seen in SLE, Sjogren’s syndrome, secondary syphillis, and hepatitis B infection

A
  1. Membranous Glomerulonephritis
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25
Q

Tendency to thrombosis

A
  1. Membranous Glomerulonephritis
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26
Q

Cellular proliferation affecting capillary walls or the glomerular basement membrane

A
  1. Membranoproliferative Glomerulonephritis
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27
Q

Gradual worsening of symptoms leading to loss of kidney function

A
  1. Chronic Glomerulonephritis
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28
Q

Progression to renal failure

A
  1. Chronic Glomerulonephritis
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29
Q

Symptoms:
Fatigue, anemia, hypertension, edema, and oliguria

A
  1. Chronic Glomerulonephritis
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30
Q

Many varieties of casts

A
  1. Chronic Glomerulonephritis
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31
Q

Markedly decreased GFR

A
  1. Chronic Glomerulonephritis
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32
Q

Increased BUN and CREATININE

A
  1. Chronic Glomerulonephritis
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33
Q

Electrolyte imbalance

A
  1. Chronic Glomerulonephritis
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34
Q

immune-mediated

A
  1. Nephritic Syndrome
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35
Q

acute onset of usually grossly visible hematuria

A
  1. Nephritic Syndrome
36
Q

RBC casts

A
  1. Nephritic Syndrome
37
Q

mild to moderate protenuria

A
  1. Nephritic Syndrome
38
Q

hypertension

A
  1. Nephritic Syndrome
  2. Nephritic Syndrome
39
Q

oliguria (decreased urine output)

A
  1. Nephritic Syndrome
40
Q

Genetic disorder showing lamellated and thinning of glomerular basementbrane.

A
  1. Alport Syndrome
41
Q

Inherited sex-linked or Autosomal

A
  1. Alport Syndrome
42
Q

Lipid nephrosis

A
  1. Minimal Change Disease
43
Q

Little cellular changes

A
  1. Minimal Change Disease
44
Q

Disruption of podocytes occuring primarily in children following allergic reactions and immunizations

A
  1. Minimal Change Disease
45
Q

Allergic reactions

A
  1. Minimal Change Disease
46
Q

Recent immunization

A
  1. Minimal Change Disease
47
Q

Human leukocyte antigen-typing

A
  1. Minimal Change Disease
48
Q

Affects the number of glomeruli

A
  1. Focal Segmental Glomerulosclerosis
49
Q

Disruption of the podocytes in certain areas of the glomerulus; others remin normal

A
  1. Focal Segmental Glomerulosclerosis
50
Q

Associated with heroin and analgesic abuse, and AIDS

A
  1. Focal Segmental Glomerulosclerosis
51
Q

Disruption of the electrical charges of the basement membrane leading to massive loss of proteins and lipids

A
52
Q

OFB – lipiduria; nephrotic syndrome

A
53
Q

> 3.5 grams per day (HEAVY PROTENURIA)

A
54
Q

RTE: Most clinically significant (> 2 RTE – TUBULAR DAMAGE)

A
55
Q

Less painful

A

CHRONIC

56
Q

Painful

A

ACUTE

57
Q

Long-lasting

A

CHRONIC

58
Q

Sudden onset

A

ACUTE

59
Q

Irreversible

A

CHRONIC

60
Q

Reversible

A

ACUTE

61
Q

Hematuria
Protenuria

A
  1. Acute PostStreptococcal Glomerulonephritis
  2. Rapidly Progressive/Crescentic Glomerulonephritis
  3. Goodpasteur Syndrome
  4. Wegener’s Granulomatosis
  5. Membranous Glomerulonephritis
  6. Membranoproliferative Glomerulonephritis
  7. Chronic Glomerulonephritis
62
Q

Oliguria – decreased urine output

A
  1. Acute PostStreptococcal Glomerulonephritis
  2. Nephritic Syndrome
63
Q

Dysmorphic RBCs

A
  1. Acute PostStreptococcal Glomerulonephritis
  2. Rapidly Progressive/Crescentic Glomerulonephritis
64
Q

RBC cast, Hyaline cast, Granular cast

A
  1. Acute PostStreptococcal Glomerulonephritis
  2. Rapidly Progressive/Crescentic Glomerulonephritis
65
Q

(+) ASO titer – anti-streptolysin O

A
  1. Acute PostStreptococcal Glomerulonephritis
66
Q

WBCs

A
  1. Acute PostStreptococcal Glomerulonephritis
  2. Rapidly Progressive/Crescentic Glomerulonephritis
67
Q

RBC Casts

A
  1. Goodpasteur Syndrome
  2. Wegener’s Granulomatosis
  3. Nephritic Syndrome
68
Q

Elevated serum creatinine and BUN

A
  1. Wegener’s Granulomatosis
69
Q

Protenuria
Hematuria with RBC Casts

A
  1. Henoch Schonlein Purpura
70
Q

Red skin patches, blood in sputum and stool

A
  1. Henoch Schonlein Purpura
71
Q

Decreased serum complement

A
  1. Membranoproliferative Glomerulonephritis
72
Q

Glucosuria (result of tubular dysfunction)

A
  1. Chronic Glomerulonephritis
73
Q

Elevated IgA levels

A
  1. IgA nephropathy/Berger’s Disease
74
Q

Acute onset of usually grossly visible hematuria

A
  1. Nephritic Syndrome
75
Q

Mild to moderate proteinuria

A
  1. Nephritic Syndrome
76
Q

Hypertension

A
  1. Nephritic Syndrome
77
Q

Microalbuminuria

A
  1. Alport Syndrome
78
Q

Heavy protenuria

A
  1. Minimal Change Disease
79
Q

Transient hematuria

A
  1. Minimal Change Disease
80
Q

Fat droplets

A
  1. Minimal Change Disease
81
Q

Protenuria
Microscopic hematuria

A
  1. Focal Segmental Glomerulosclerosis
82
Q

Heavy proteinuria
Hematuria

A
  1. Nephrotic Syndrome
83
Q

Renal tubular cells

A
  1. Nephrotic Syndrome
84
Q

OFB

A
  1. Nephrotic Syndrome
85
Q

Fatty and waxy casts

A
  1. Nephrotic Syndrome