Renal Flashcards

1
Q

Primary function of the kidneys

A

Maintain a stable internal environment for optimal cell and tissue metabolism

1) balancing solute and water transport
2) excrete metabolic waste products
3) conserving nutrients
4) Regulating acids and bases

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2
Q

What is the kidneys endocrine function

A

Secreting the hormone rennin - regulates blood pressure

Erythropoietin- needed for RBC production

125 hydroxy vitamin D3 - metabolizes calcium

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3
Q

What is gluconeogenesis

A

Synthesizing glucose from amino acid

I’m times of severe fasting

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4
Q

Juxtaglomerular cells secrete what?

A

Renin

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5
Q

Macula Densa sense changes in what?

A

Sodium

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6
Q

What happens to cause the urge to void

A

When the bladder has enough urine (250-300 ccs in an adult)
A micturition reflex occurs which allows urination
This reflex is triggered by an activation of the spinal reflex arc (occurs when the bladder contracts and the internal urethral sphincter relaxes. - this causes the urge to void

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7
Q

Potty training

A

The reflex to void can be inhibited or facilitated by impulse from the brain resulting in voluntary control of micturition

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8
Q

GFR

A

Tells us how well the kidneys work

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9
Q

GFR is directly related to _______

A

Renal blood flow

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10
Q

Changes in systemic blood pressure or blood volume will induce

A

Changes in arteriole resistance or pressure to maintain a constant GFR

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11
Q

If there is a rise in systemic Bp, the afferent arterioles

A

Constrict preventing an increase in glomerular blood flow and filtration pressure keeping the GFR the same

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