Regulation of body fluid compartments Flashcards
What percentage of the body is water?
60%
How is the water distributed?
40% body weight intracellular, 20% body weight extracellular. 60% of total bodyweight
How is the 20% extracellular distributed?
80% interstitial fluid
20% Plasma
What is the osmolality of ECF?
290m/osm
What mechanisms regulate body fluid comparments?
Both up and down
- Osmolality HYPOTHALAMUS. If the osmolality is too high then ADH is released and vice versa
- Volume - Baroreceptors in the aortic arch and carotid sinus measure BP. If it is too low then the aldosterone pathway is initiated. If it is too high then ANP is released
What does hypoosmotic contraction look like?
eg salt wasting
what does hypoosmotic expansion look like?
Eg too much ADH - SIADH
what does hyperosmotic expansion look like?
eg Increased Na
what does hypersmotic contraction look like?
eg sweating
what does isoosmotic expansion look like?
eg too much Hartmanns
what does isoosmotic contraction look like?
eg cholera