Receptors, Receptor Complexes & Signal Transducers Flashcards
1
Q
What is the structure of a receptor like?
A
- discriminator domain: binds to ligand, discriminates between the ligand types
- effector domain: produces signals
2
Q
What are antagonists?
A
Ligands which stabilise the inactive conformation of the receptor
3
Q
What are agonists?
A
Molecules which stabilise the active conformation of the receptor
4
Q
How do ligand-activated transcription regulators work?
A
- require ligand to dimerise
- require ligand to bind DNA
