RBC INCLUSION

Question 1

-nuclear remnants of DNA
-associated with Megaloblastic anemia, thalassemia, myelodysplastic anemia

Answer 1

Howell Jolly bodies

Question 2

-Precipitation of RNA
-“blue berry bagel appearance”
-associated with
lead poisoning
megaloblastic anemia
myelodysplastic syndrome

Answer 2

Basophilic stippling

Question 3

-Remnants of microtubules of mitotic spindles
-rings looplike figure of eight

Answer 3

Cabot ring

Question 4

-Precipitated, denatured hemoglobin due to oxidative injury
-appearance of pitted GOLF BALL
-cannot be seen in wright’s stain
-associated with
G6PD deficiency
hereditary defects
favism- sensitivity to fava beans

Answer 4

HEINZ BODIES

Question 5

-stains with Pearl’s prussian blue
-common for sideroblastic anemia

Answer 5

Pappenheimer bodies/ siderotic granules

Question 6

imparts GOLF BALL appearance
-demonstrated with a supravital stain: Brilliant cresyl blue

Answer 6

Hemoglobin H

Question 7

-hexagonal with blunt ends
-Barr of gold/ clam shell appearance

Answer 7

Hb C or CC crystals

Question 8

-washington monument crystal
-crystalline fingerlike/quartzlike

Answer 8

Hb SC crystals

Question 9

-Nucleated RBC that contains non heme iron particles

Answer 9

ringed sideroblast