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RANDOm Flashcards

1
Q

prednisolone

A

osteoporosis

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2
Q

retinopathy a side effect for

A

hydroxychloroquine

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3
Q

oligospermia a side effect for

A

sulfasalazine

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4
Q

gold

A

nephrotoxic

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5
Q

methotrexate causes

A

pneumonitis

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6
Q

Padder Willi

A

15 Q

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7
Q

Angleman

A

15Q

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8
Q

what antipsychotic would you give in diabetics and hypertensives

A

rispiridone

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9
Q

antipsychotic for parkinsons (or lewy bodies)

A

quetiapine

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10
Q

post MI pain

A

Morphine

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11
Q

howell jolly body

A

hypospenism

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12
Q

DIC

A

D dimer - most diagnostic other than coag screen

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13
Q

target cells

A

Beta thal

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14
Q

acute phase protein

A

serum ferritin

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15
Q

iron absorption

A

at duodenum

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16
Q

B12 ABSORPTION

A

ileum

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17
Q

folate absorption

A

duodenum or jejunum

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18
Q

hydroxycarbamide

A

HbA promotion in sickle cell

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19
Q

folic acid

A

promote RBC production

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20
Q

penicillin in sickle cell

A

to decrease risk of hyposplenism

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21
Q

treatment for huntingtons

A

tetrabenazine

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22
Q

ADHD and a tic

A

clonidine

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23
Q

anti VGCC

A

LEMS

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24
Q

tX for lems

A

3,4-diaminopyridine

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25
Q

GBS

A

demylinating disorder most commonly caused by recent campylobacter infection

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26
Q

GBS progression

A

Progressive symmetrical sensorimotor paralysis - ascending
will be areflexia
usually stops progressing after four weeks

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27
Q

complex regional pain

A

post surgery or minor injury

will be leg swelling, skin changes and motor dysfunction

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28
Q

Central post stroke pain

A

hemiplegia with initial paraesthesia followed b allodynia

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29
Q

Tx for alzheimers

A

donepezil, galantamine or rivastigmine

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30
Q

S+s for frontotemporal

A

inhibtion, apathy, difficulty planning

- semantic dementia or progressive non-fluent aphasia

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31
Q

semantic dementia

A

word finding difficulty - loss of recognition of familiar faces or objects

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32
Q

Progressive non-fluent aphasia

A

slow/hesitiant speech, word finding deficits and agrammatism

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33
Q

Ix for vascular

A

SPECT

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34
Q

S+s for vascular

A

attentional impairment, disinhibition, cognitive slowing, fnd and difficulty walking/falls

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35
Q

MS UMN OR LMN

A

UMN - affecting the white matter tracts of the brain and spinal cord

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36
Q

Lhermitte sign

A

an electrical shock-like sensation down the upper limbs and trunk on neck flexion

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37
Q

Uhtoff’s phenomenon

A

exacerbation of current symptoms in hot environments

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38
Q

triad of what in MS

A

sensory
ocular
motor aka pyramidal
with get other Sx such as; cerebellar dysfunction, fatigue and LURTdysfunction

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39
Q

Ix for MS

A

MRI and LP

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40
Q

sensory sx tx for MS

A

gabapentin

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41
Q

spasticity tx for MS

A

baclofen

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42
Q

trigeminal neuralgia tx

A

carbamazepine

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43
Q

associations of myasthenia gravis

A

thymic hyperplasia
thymoma
SLE
hyperthyroid

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44
Q

Ix for myasthenia

A

Anti Ach and Anti MUSK
TFT
CT

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45
Q

Tx for myasthenia

A

pyridostigmine (anticholinesterase), thymectomy, IV immunoglobulins - short
long - immunosuppression with high dose and steroid paring +plasma exchange

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46
Q

cause of lems

A

lung cancer

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47
Q

gait in lems

A

waddling as proximal weakness

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48
Q

myasthenia feature

A

end of day weakness, occular weakness,
proximal more marked than distal
weak facial/expressive/respiratory muscles

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49
Q

inverted champagne bottles of lower limbs

A

charcot-marie tooth disease

50
Q

anomic aphasia - angular gyrus

A

impaired ability to find words everything else is normal

51
Q

affective responsiveness

A

ability of an individual to respond to emotional needs of another family member

52
Q

egocentrism

A

only ale to consider their own point of view and see it as the only possible

53
Q

anxious avoidant attachment

A

child avoids/ignores parent with little emotional response

54
Q

anxious ambivalent

A

distressed without caregiver - explores little

a bit warOy of strangers

55
Q

affective responsiveness

A

the ability of an individual to respond to the emotional needs of another family member

56
Q

OA stiffness

A

<30 mins in morning

57
Q

NT for sleep

A

serotonin

58
Q

NT disrupted by haloperidol

A

dopamine

59
Q

tardive dyskinesias

A

typical antipsychotics

60
Q

weight gain

A

olanzapine

61
Q

underactive thyroid

A

lithium

62
Q

Na val side effects

A

stomach irritation, unsteady, tremor and weight gain

63
Q

prophylaxis in asthma

A

topiramate

64
Q

eating disorder med

A

fluoxetine

65
Q

factitious disorder

A

fake symptom for no obvious reason

66
Q

dissociative disorder

A

a random somatic symptom as presentation for an alternative life event

67
Q

hyperthermia, hypertension and tachy

A

cocaine

68
Q

psychotic, weakness, tremor and arrhythmia

A

amphetatmine

69
Q

pinpoint pupil, decreased resp and LOC

A

opioid overdose - naloxone

70
Q

mild depression

A

at least 2 core criteria for 2 weeks

71
Q

moderate depression

A

2 and 4 (half of 4 is two)

72
Q

severe depression

A

3 and 5

73
Q

eating something random like soap

A

pica

74
Q

antidepressant in preg

A

sertraline

75
Q

Loop of Meynert

A

Alzheimers

76
Q

Dx for Alzheimers

A

MMSE

77
Q

Picks Dx

A

CT scan

78
Q

Hachinski ischaemia score

A

used to differentiate different types of dementia

79
Q

initiates abduction

A

supraspinatus

80
Q

up to 90 degress of abduction

A

deltoid

81
Q

abduction beyond 90 degrees for arm

A

trapezius and serratus anterior

82
Q

winging of scapula

A

long thoracic

83
Q

finger flexion

A

median

84
Q

finger extension

A

radial

85
Q

axillary sign and cause

A

cant abduct following humeral fracture

86
Q

ulnar c and s

A

claw hand after medial epicondyle fracture

87
Q

radial s and c

A

wrist drop following humeral fracture

88
Q

gram positive meningitis

A

lysteria

89
Q

a homeless alcoholic has meningitis

A

CMV meningitis

90
Q

Glycoprotein IIB/IIIA

A

Abciximab

91
Q

Phsophodiesterase inhibitor reducing production of cAMP

A

dipyridamole

92
Q

acute inflammatory cells

A

neutrophils

93
Q

eosinophils

A

parasites

94
Q

EBV infection

A

atypical lymphocytes

95
Q

Glutathione

A

antioxidant

96
Q

Krebs cycle

A

main pathway for ATP

97
Q

high affinity for oxygen

A

2,3-DPG

98
Q

G6PD

A

glucose hexose monophosphate pathway

99
Q

geriatric pharmacodynamics - more acidic of basic

A

basic
due to increased gastric pH
decreased body water content
increased body fat

100
Q

lipophilic drugs have a decreased vd of lipophilic drugs t or f

A

f

have an increased vd due to increased body fat etc

101
Q

metabolism in elderly unchanged?

A

will decrease due to small liver
decreased first pass
decreased binding enzymes

102
Q

albumin binds to what

A

acidic things

103
Q

A1 acic glycogen binds to what

A

basic things `

104
Q

can you use serum creatinine as a reliable measure of GFR in elderly

A

no - often underestimates

however GFR is usually reduced in elederly anyway

105
Q

why are bb not as effective / need more of in the elderly in comparison to any other med where you need less to have an affect

A

decreased first pass metabolism

106
Q

sie effect of opiods

A

constipation - start senna prophylactically

107
Q

criteria used for geriatric med risk

A

BEERS citeria

108
Q

meds to stop

A 
codeine 
loperamide 
prochlorezapine 
metocopramide 
stimulant laxatives
109
Q

meds to start

A

PPI
fibre supp
anti hyp (consider CCB or BB if coexisting angina)
Warfarin or DOAC

110
Q

OA tx

A

PARACETAMOL

111
Q

RA and splenomegaly

A

Feltys

112
Q

Leukoerythroblasts

A

Idiopathic myelofibrosis

113
Q

Low platelets and normal marrow

A

ITP

114
Q

Ix for multiple myeloma

A

protein/serum electrophoresis

115
Q

Sickle cell Ix

A

HPLC

116
Q

smear cell

A

CML

117
Q

yolk sac produces

A

AFP

118
Q

choriocarcinoma produces

A

HCG

119
Q

theca produces

A

androgens

120
Q

granulosa

A

oestrogens

121
Q

Abdo mass, heavy bleeding

A

fibroid or cancer

Neuro (17 decks)

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