r e s p C P T

Question 1

how do B agonists work and what are their side effects

Answer 1

act as bronchial b2 receptors, causing smooth muscle relaxation and reduce mucus secretion

causes tremors, tachycardia

Question 2

give examples of SABA and LABA and how long they act

Answer 2

2-4hrs
salbutamol = ventolin

12-18hrs
salmeterol - serevent
formoterol

Question 3

how do muscaranic agents act and what are the associated side effects

Answer 3

cause bronchodilation
and reduce mucus secretion

dry mouth

Question 4

give example of short acting and long acting muscarinic antagonists

Answer 4

3-6hrs = ipraptroium = SAMA
tiopropium  = LAMA

Question 5

what are contraindications for use of muscuranic antagonists

Answer 5

caution in

closed angle glaucoma
BPH

Question 6

what are the interactions seen in SABA

Answer 6

causes hypokalaemia in high doses

interact w corticosteroids, loop/thiazide diuretics, theophylline

Question 7

descrine the MOA of theophylline and aminophylline

Answer 7

methylxanthines

PDE inhibitors
increase cAMP and cause bronchodilation

Question 8

what are the side effects of aminophylline and theophylline

Answer 8

nausea
arrhythmias
seizures
reduced K

Question 9

what drug type and MOA of montelukast

Answer 9

leukotriene receptor antagonist

blocs cysteinyl leukotrienes

Question 10

name a mucolytic and contraindication

Answer 10

carbocysteine
active peptic ulceration CL
used in copd