Quiz 1, Sept 25

Question 1

lisinopril

Answer 1

-Prinivil, Zestril

• Antihypertensive
• suppression of the renin-angiotensin-aldosterone system
• Angiotensin converting enzyme (ACE) inhibitor

dizziness, hypotension, fatigue, cough

Question 2

simvastatin

Answer 2

-Zocor

• Antihyperlipidemic
• specific inhibitor of HMG-coA reductase

Muscle pain, dysepepsia, constipation

Question 3

albuterol sulfate (inhalation)

Answer 3

-Proventil HFA, Proair HFA, Ventolin HFA

• Antiasthmatic
• Catalyze formation of c-3,5 AMP from ATP which causes the relaxation of Bronchial,uterine and vascular smooth muscle through stimulation of Beta-2-adrenergic receptors.
• Beta 2 agonist

-Nervousness, insomnia, tremor, tachycardia & palpitations

Question 4

amlodipine besylate

Answer 4

Norvasc

Antihyperntetive
-calcium channel blocker tha inhibits influx of calcium ions in specific cellular membranes

Edema, flushing

Question 5

Hydrochlorothiazide

Answer 5

Microzide

Diuretic

Inhibits reabsoption of sodium and chloride at the distal renal tube.

Dryouth, muscle cramps, weakness orthostatic hypotension

Question 6

tramadol

Answer 6

Ultram (ER), Ryzolt

Analgesic, Opioid

centrally acting synthetic analgesic; binds to m-opioid receptor and inhibition of reuptake of norepinephrine and serotonin

somnolence, dizziness, vomiting, pruritus, dyspepsia

Question 7

levothyroxine [sodium]

Answer 7

Synthroid, Levoxyl, Levothroid

hormone/thyroid

exact mechanism of L-thyroxine unknown; protein synthesis control

rare, over dose leads to hypermetabolic statesv - fever, hypoglycemia, heart failure, fluid loss, tachycardia

Question 8

metformin Hydrochloride

Answer 8

Glucophage (XR)

• antidiabetic
• biguanide(improves glucose tolerance in NIDDM patients)
• decreases intestinal absorption of glucose.
• suppresses hepatic gluconeogenesis
• improve glucose sensitivity

decreased B12 absorption, LACTIC ACIDOSIS

Question 9

furosemide

Answer 9

-Lasix

• diuretic
• loop diuretic inhibits reabsorption of Na/Cl in proximal and distal tubules

orthostatic hypotension, HEARING LOSS, WEAKNESS, MUSCLE CRAMPS, ANEMIA

Question 10

Atorvastatin calcium

Answer 10

Lipitor

• antihyperlipidimic
• selective competitive inhibitor ofHMG CoA reductase
• responsible for the conversion of HMg CoA to mavelonate an early rate limiting step in the synthesis of cholesterol

Dyspepsia and flatulence

Question 11

alprazolam

Answer 11

Xanax

• anti anxiety agent
• Benzodiazepines facilitate the inhibitory neurotransmitter action of gamma-aminobutyric acid (GABA), which mediates both pre- and post-synaptic inhibition in all regions of the CNS.
• enhances inhibitory effect of GABA
• drowsiness and hypotension I

Question 12

Hydrocodone (bitartrate) with acetaminophen

Answer 12

Opioid analgesic

• Lortab, Vicodin, lorcet, Norco
• inhibits prostagGlandin synthesis in CNS & blocks pain impulse generation

Drowsiness , dizziness