Questions- Wrongies From Papers Flashcards

1
Q

State four clinical signs consistent with acute ischaemia in a limb?

A

Paralysis, pallor, paraesthesia and pulselessness

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2
Q

State four cardiovascular compensatory mechanisms mediated by the SNS in hypovolaemic shock.

A

Vasoconstriction, increased HR, increased SV and positive inotropy

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3
Q

Give an anatomical explanation for the “Hand of benediction”

A

Failure of Flexion of the index and middle fingers: paralysis of the FDS, FDP and lumbricals to index and middle fingers, supplied by median nerve.
Intact Flexion of ring and little fingers: intact inner action of the FDP and lumbricals to ring and little fingers, supplied by ulnar nerve
Thumb is adducted: intact innervation to adductor pollicis, supplied by ulnar nerve
Thumb is extended at IPJs: intact innervation to extensor pollicis longus, supplied by the radial nerve

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4
Q

Describe how the normal ventricular septum forms

A

The muscular portion grows upwards from the floor of ventricles
The membranous portion is derived from the endocardial cushions and grows downwards to fuse with the muscular portion

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5
Q

Name two of the hallmarks of cancer and describe how each of these characteristics benefit the cancer cell

A

Self sufficient in growth signals, tumours have the capacity to proliferate without external stimuli- cell has proliferation advantage
Resistance to apoptosis- cell has a survival advantage

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6
Q

Give three specific examples of things that may cause damage to DNA and subsequent tumourigenesis

A

UV radiation
X ray
Obesity

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7
Q

Give two reasons why a woman in late pregnancy is predisposed to DVT

A

The presence of a pelvic mass- compresses venous outflow from the legs resulting in venous stasis
The patient may be less mobile than usual leading to venous stasis

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8
Q

What is an embolism?

A

The blockage of a blood vessel by a solid, liquid or gas at a site distant from its origin

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9
Q

What is a saddle embolus?

A

A large embolus that straddles the bifurcation of an artery

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10
Q

Apart from thrombi, state two things that can embolise

A

Air

Amniotic fluid

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11
Q

State three actions that should be taken to reduce to risk of transmitting a diarrhoeal infection

A

Nurse the patient in a side room
Hand washing with soap and water before and after seeing the patient
Wear gloves

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12
Q

What two virulence factors does C.difficile have that causes diarrhoea? Explain how they cause diarrhoea

A

Toxin A- an enterotoxin that causes excessive fluid secretion
Toxin B- a cytotoxin that damages protein synthesis and cell structure

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13
Q

Give precise names for two anatomical structures that usually contribute to the stability of the hip joint and that are likely to be affected during a total hip replacement

A

Joint capsule and iliofemoral joint

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14
Q

State in order the sequence of vessels a catheter will pass through to reach the coronary artery.

A

External iliac artery, common iliac artery and aorta

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15
Q

Where is the opening of the left coronary artery located?

A

Left aortic sinus just above the left leaflet of aortic valve

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16
Q

Name one hormone involved in the mobilisation of TAGs from fat stored and the enzyme involved in this process and the resulting products

A

Glucagon
Hormone sensitive lipase
Fatty acids and glycerol

17
Q

Name four bacteria that can cause pneumonia

A

Streptococcus pneumoniae
Staphylococcus aureus
Haemophilus influenzae
Moraxella catarrhalis

18
Q

Describe the role played by CRP in fighting infection

A

CRP acts as an opsonin by binding to molecules on the surface of bacteria initiating phagocytosis