Pulmonary Vascular Disease Flashcards
1
Q
What is another name for adult respiratory distress syndrome (ARDS)?
A
Shock lung.
2
Q
What are the causes of ARDS?
A
Sepsis, diffuse infection (virus, mycoplasma), severe trauma, oxygen.
3
Q
Describe the pathogensis of ARDS.
A
Injury e.g. bacterial endotoxin leads to infiltration of inflammatory cells -> cytokines -> oxygen free radicals -> injury to cell membranes.
4
Q
What does tissue with ARDS look like?
A
Has a fibrinous exudate lining alveolar walls (hyaline membranes), cellular regeneration, inflammation.
5
Q
What are the 3 possible outcomes of ARDS?
A
Death, resolution, fibrosis (chronic restrictive lung disease).
