PSY2003 W1 Schizophrenia 2 - R

Question 1

What did Thompson et al. use to study gray matter in schizophrenia?

Answer 1

Brian mapping algorithms of anatomical profiles

Question 2

What did Thompson et al. detect ?

Answer 2

Aceelerated grey matter loss in very early-onset schizophrenia

Question 3

Where was the earliest deficits founds?

Answer 3

In parietal brain region (visuospatial and associative thinking)

Question 4

Where was the next deficit found?

Answer 4

anteriorly into temporal lobes (sensorimotor and dorsolateral prefrontal cortices and frontal eye fields)

Question 5

What did the deficits visible in the brain mapping correlated with?

Answer 5

with the psychotic symptom severity and reflected the impairments in the disease (neuromotor, auditory, visual search and frontal executive impairments)

Question 6

What is the typical onset of schizophrenia

Answer 6

Late adolescence/early adulthood

Question 7

What is a early-onset of schizophrenia like?

Answer 7

Childhood onset schizophrenia is a sever form of the disorder

Question 8

What were the results of gray matter loss for normal adolescents ?

Answer 8

There was a subtle but significant change detected in normal adolescents.

Question 9

What were the results for the schizophrenic patients?

Answer 9

striking accelerated loss of grey matter in the frontal eye fields and supplementary motor, sensorimotor, parietal and temporal cortices in both brain hemisphere