Protein functional diversity Flashcards
Characteristics of globular proteins?
- functional
- water soluble
- usually spherical - tertiary structure critical to function
- weaker
Characteristics of fibrous proteins
- structural
- not water solube
- elongated
- stronger, and more beta pleated sheets
Why are proteins functionally diverse?
many combinations of amino acids are possible. This can form many proteins with diverse structures, and therefore functions.
7 main types of proteins?
SHIT CRE(E)
Structural - fibrous support tissue in skin, bone (collagen/keratin)
Hormone - regulates body acivities (insulin)
Immunoglobulin - defence against disease (antibodies)
Transport - carries other molecules (haemoglobin)
Contractile proteins - facilitate muscle movement (myosin)
Receptor molecule - responds to stimuli (eg. insulin receptors)
Enzyme - catalyses reactions (lactase)
why are globular proteins water soluble and fibrous proteins not?
in globular proteins, amino acids with polar side chains tend to point outwards - they can interact with water and dissolve . Fibrous -> inwards -> can’t interact