Prostaglandin Synthesis

Question 1

Cox 1

Answer 1

increases blood flow to kidney
protect stomach
trigger vasoconstriction
increase ability to clot

Question 2

Cox 2

Answer 2

produce prostaglandins
trigger inflammation and vasodilation

Question 3

1st generation NSAID

Answer 3

blocks cox 1 and 2

decreases blood flow
GI bleeding
trigger vasodilation
decrease ability to clot

Question 4

2nd generation NSAID

Answer 4

blocks cox 2 (Celebrex)

block prostaglandin production

Question 5

Inflammation Process Step 1

Answer 5

• where the injury is located histamines are released from mast cells
• prostaglandins follow the histamines and trap the area (encourages blood flow)

Question 6

Inflammation Process Step 2

Answer 6

• capillaries start to dilate
• sending more blood flow and o2 to the injury site

Question 7

Inflammation Process Step 3

Answer 7

• chemotadic factors follow to the site and attract phagocytic cells
• help contain and heal area

Question 8

Inflammation Process Step 4

Answer 8

Acute: 7-10 days phagocytes go back and consume leftover pathogens and debris