Primary CVD prevention: debunking myths Flashcards
Impact of HTN on CV system
1) incr resistance to flow and vasoconstriction
2) accel atherosclerosis
effect of HTN on heart structure
LVH –> LV dilation –> HF
___ is the #1 risk factor for heart failure
hypertension
older you are, higher the risk
what is #1 risk factor for stroke in US?
systolic blood pressure
lowering ____ reduces risk of stroke, MI, and CV death at any age
systolic blood pressure
Big 4 CVD risk factors
1) smoking
2) DM
3) HTN
4) dyslipidemia
how have CVD deaths changed over last 20 yrs
40% decr
what factors have most contributed to 40% decline in CVD mortality in last decade?
1) BP control
2) lipid control
myth #1: raising HDL with drug saves lives
no benefits in high risk (DM and CAD) patients by incr HDL
risk is not improved BEYOND a certain point
good Effects of statins
1) lower CV disease (primary and secondary)
a
a
a
a
a
a
bad effects of statins
risk of muscle pain
incr blood sugar and HbA1c
potential for non-serious/reverisble cognitive
a
a
a
a
role of glycemic control in decr CV risk in diabetics
intense glucose control had no effect on macrovascular disease but does improve microvascular disease and incr risk of CVD death
a
A
a
a
if glycemic control not beneficial, what should we focus on?
tight systolic BP control
