Pregnancy and lactation Flashcards
OTC drugs to avoid in constipation in pregnancy
Mineral and castor oil
For GERD in pregnancy, avoid what 2 drugs?
Sodium bicarbonate and gaviscon
How to treat hemorrhoids in pregnancy?
Fiber, fluid, sitz baths, laxatives and stool softeners.
3 Symptom relief options for hemorrhoids in pregnancy:
Topical lidocaine, witch hazel, hydrocortisone
4 Nausea and vomiting therapy options in pregnancy
Diclegis, Reglan, zofran, and ginger
Options for hyperemesis gravidarum, list risk too
Dexamethasone and prednisolone, risk of oral cleft
First line for gestational diabetes
Insulin
Second line for gestational diabetes
Glyburide
Pregnancy term for hypertension with proteinuria
Pre-eclampsia
Definition of eclampsia
Hypertension with proteinuria with seizures
Definition of hypertension in pregnancy
90 diastolic BP from 2 readings
for women at risk of pre-eclampsia, _____ after 12 weeks gestation reduces risk. When to stop?
81 mg aspirin. Talk with doctor about risk vs benefit.
What supplement at what dose reduces hypertension and pre-eclampsia risk in pregnancy?
Calcium 1 gram per day
What supplement is used to prevent progression from pre-eclampsia to eclampsia and to treat eclamptic seizures?
Magnesium sulfate
Avoid which 2 drugs in eclamptic seizures?
Diazepam and phenytoin
What to do about gestational hyperthyroid?
Nothing, usually resolves after 20 weeks gestation
When is ibuprofen (all NSAIDS) contraindicated in pregnancy?
1st and 3rd trimester
OTC option for tension headache in pregnancy?
Tylenol or ibuprofen (not 1st or 3rd trimester)
What to take for migraine associated nausea in pregnancy?
Promethazine, reglan, or compazine
Used in pregnancy with severe headaches not responsive to other treatments:
Propranolol low dose as preventative
Drug of choice for asymptomatic bacteriuria in pregnancy
Cephalexin
When and why to avoid macrobid during pregnancy
After 37 weeks due to risk for hemolytic anemia
When to use Bactrim for UTI in pregnancy
Don’t
When during gestation is cipro best for UTI treatment?
Never
Why are tetracyclines contraindicated during pregnancy?
Bone malformations
Herpes treatment in pregnancy
Acyclovir
Treatment of choice for yeast infection in pregnancy
Topical / intravaginal antifungals
Oral treatment of choice for yeast infection in pregnancy, risks associated
Terbinafine or fluconazole 150 mg. Fluconazole very low risk of spontaneous abortion in first trimester. Risk increases with higher doses.
Preferred inhaled corticosteroid in asthma in pregnancy
Budesonide
What steroids are recommended in severe asthma during pregnancy?
Systemic
First line for runny nose and congestion in pregnancy
Nasal Beclomethasone or budesonide
Can Afrin be used for congestion in pregnancy?
Yes
Drug of choice for diabetes during pregnancy
Insulin
Insulin initiation dosing in pregnancy
0.7 to 1 unit per kg per day divided
Which are the safest 2 anti seizure meds in pregnancy?
Lamotrigine and carbamazepine
Tegretol and lamictal can cause what birth defect?
Cleft palate
If anti seizure meds will be stopped prior to conception, how long before must they be stopped?
6 months
All women with epilepsy should take folic acid at what dose daily?
4-5 mg
Drug therapy is indicated for blood pressure in pregnancy of _____
160/110
Drug of choice for HTN in pregnancy
Labetalol
Why choose Slynd over other progestin only pills?
Can miss a day without as much risk as other POP’s
Orilissa
Elagolix
Elagolix
Orilissa
Elagolix MOA
GNRH antagonist
Elagolix indication
Endometriosis
Elagolix 4 common side effects
Amenorrhea, hot flashes, nausea, headache, BMD decrease
Uncomplicated acute UTI in pregnancy 2 empiric antibiotics of choice:
Augmentin or cefpodoxime
What formulation of dextromethorphan should be avoided in pregnancy?
Liquids with ethanol
What cough med otc is okay in pregnancy?
Dextromethorphan and guaifenesin
Safest topical pain relief in pregnancy?
Lidocaine
Safest oral pain relief in pregnancy? Duration?
Tylenol, not chronic use.
OTC Topical pain relief option after delivery
Dermoplast spray (benzocaine)
How does estrogen increase clot risk?
It stimulates clotting protein production in the liver