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PHRM 844 Exam 2 > Posterior Pituitary - Park > Flashcards

Posterior Pituitary - Park Flashcards

1
Q

Posterior Pituitary Hormones

A

vasopressin (ADH)

oxytocin

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2
Q

Desmopressin

A

vasopressin analog
high half life
minimal V1 activity > no increased blood pressure

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3
Q

V1

A

vasopressin receptor that increases cytosolic calcium

causes vasoconstriction

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4
Q

V2

A

vasopressin receptor that increases cAMP

increases aquaporins leading to water reabsorption

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5
Q

Clinical uses for vaso/desmopressin

A

diabetes insipidus
noctural enuresis
coagulopathy

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6
Q

Vasopressin antagonists

A

treat hyponatremia
conivaptan
talvaptan

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7
Q

Oxytocin

A

labor stimulating
milk ejection
AE - excessive contraction, vasopressin activation

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8
Q

CIs to oxytocin use

A

fetal distress
previous uterine rupture or procedure
abnormal fetal presentation

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PHRM 844 Exam 2 (10 decks)

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