Portal Hypertension Flashcards
1
Q
portal system
A
- area where the exchange takes place and starts in venous and ends in venous
- 2 portal system
- in the gut ends in the liver (hepatic portal system)
- starts at the hypothalamus and ends in the pituitary (hypothalamus hypophyseal system) - Anastomosis of portal & systemic -blood bypass liver - liver function decreases (porto cable shunting)
2
Q
PORTAL HYPERTENSION
A
- PORTAL PRESSURE 12 mmHG or»_space;
- Increased intrahepatic resistance // increased portal venous inflow
- CIRRHOSIS due to portal hypertension
3
Q
PATHOPHYSIOLOGY
A
-
HEPATIC VASCULAR RESISTANCE
- Architectural distortion (in cirrhosis)
*regenerative nodule- activated stellate cells
-Compression by hepatic venules
- activated stellate cells
- Architectural distortion (in cirrhosis)
-
INCREASE PORTAL VENOUS INFLOW
- cirrhosis
- increase vasodilators
4
Q
COMPLICATION
A
-Hematemesis // melena
-Lethargy
-Increase abdominal girth
- Abdominal pain & fever