Pig nervous sytem Flashcards
What do all causes of congenital tremors lead to
Hypomyelinogenesis, cerebellar hypoplasia
Then get mortality due to difficulty feeding and squashing
What is the most common infectious cause of congenital tremor
Atypical porcine pestivirus; exposure in utero
Must make sure breeding females are exposed BEFORE entering breeding herd
What are congenital A1 tremors assocaited wtih
Classical swine fever; due to sow infection at 10-50days gestation so piglets become persistently viraemic
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What do piglets that survive congential tremors look like a few months later
Mild tremor /nystagmus only
Genetic association of congenital tremor
A3 = inhertied, male sex linked, associated with landrace breed A4 = inherited in Saddlebacks
Clinical signs, treatment and diagnosis of neonatal hypoglycaemia
Signs: weak, shivering pigs, tremors, ataxia, collapse, convulsions
Diagnosis = blood glucose <2.8mM
Treat with 15ml 20% glucose intraperitoneal injection
What is more common out of salt poisoning and water deprivation
Water deprivation much more common
Signs of salt poisoning/water deprivation
UNsettled, blidnness, ataxia, head pressing, consulions, drinking puddlings
Histology shows characteristics eosinophilic meningitis
Why must we add water back slowly after water deprivation
Too fast will cause cerebral oedema
What disease does strep suis cause in preweaning pigs and which serotype
Serotype 1
Ill thrift, fever, polyarthris, septicaemia, meningitis etc
What disease does strep suis cause in weaned pigs
Key one = meningitis; up to a week post-stress event
= ataxia, incoordination, convulsions etc
- Found dead
- Polyarthiris and lameness
- PLeuropneumonia with fibrin and dyspnoea
What signs cam zoonotic strep suis infection cause in humans
- Fever
- Deafness
- Meningitis
etc
Treating strep suis
Parenteral amoxicillin fr clinically infected and water metaphylaxis for whole group for 5 days
Can we vaccinate for strep suis
No commercial vaccine
- But can do autogenous vaccines; wait until after weaning to avoid mAb interference
Get natural immunity via gilt acclimitisation
What might be a cause of hind limb ataxia and weakness in pigs that have been tail biting
Pelvic abscesses
What organisms are implicated in abscess formation in pigs
T pyogenes, Strep suis, S aureus, F necrophorum
What type of pathogen causes aujesky’s disease
SHV1 alpha herpesvirus
Aujeszky disease how does it work
Get replication in the nose causing fibrinonectrotic rhinitis + goes down to lung epithelial cells causing necrotic bronchitis and alveolitis
Get latency in trigeminal ganglion + lymph nodes
What are the clinical signs of Aujesky’s like in different age group pigs
Adults mostly reproductive disease
Growers mostly respiratory disease; cough, dyspnoea, pneumonia etc
Weaners: CNS and resp
Piglets: CNS, respiratory, enteric