Pharmacology 2 Flashcards
Name the two types of Cholinergic receptors
Nicotinic & Muscarinic
State the main location for Nicotinic receptors
Adrenal medullae,
Neuromuscular junction: skeletal muscle
State the main location for Muscarinic receptors
Parasympathetic effectors (smooth & cardiac muscle, lungs, glands)
Sweat glands,
Skeletal muscle blood vessels
What neurotransmitter is associated with Cholinergic receptors
Acetylcholine (ACh)
State which section of the ANS would be affected by medications that either stimulate or inhibit Cholinergic receptors
Parasympathetic
What is the effect of administering an agonist medication on Cholinergic receptors
Stimulate parasympathetic response (SLUDD)
What is the effect of administering an antagonist medication on Cholinergic receptors
(Anticholinergic) block the parasympathetic response - decreased secretions
Name the four Adrenergic receptors
a1, a2, b1, b2
State the main location for each receptor
a1: heart, vascular smooth muscle, smooth muscle in iris, sweat glands.
a2: platelets, pre synapse
b1: Heart (cardiac muscle)
b2: bronchial smooth muscle, liver, uterus
Name the two hormones that activate adrenergic receptors
Adrenaline & noradrenaline
State which section of the ANS would be affected by medications that stimulate or inhibit adrenergic receptors
Sympathetic
Describe the effect of administering an agonist medication on adrenergic receptors
Mimicks the natural effect of neurotransmitters or hormones
Describe the effect of administering an antagonist medication on adrenergic receptors
Block the receptors and prevent natural neurotransmitters or hormones from exerting an effect
Give an example of a medication that is adrenergic agonist (sympathomimetic)
Adrenaline & Noradrenaline
Give an example of a medication that is adrenergic antagonist (sympatholytic)
Beta blockers
What effect would a sympathomimetic drug have on adrenergic receptors
Increased BP HR and bronchodilation etc
What effect would a sympatholytic drug have on adrenergic receptors
Decreased BP, HR - slowing of impulse through AV node.
Decreased
what is SLUDD
parasympathetic response that includes:
Salivation,
Lacrimation,
Urination,
Digestion,
Defecation.
What are the three decreases of the parasympathetic NS
DECREASED HR, airway diameter, pupil diameter
