Pentose Phosphate Pathway

Question 1

key regulatory enzyme in PPP

Answer 1

Glucose-6-phosphate dehydrogenase

Question 2

key product of PPP

Answer 2

NADPH

Question 3

What is the role of PPP?

Answer 3

generates NADPH for reductive biosynthesis, provides cell with Ribose-5-Phosphate for nucleotide and nucleic acid synthesis

Question 4

is PPP catabolic or anabolic?

Answer 4

primarily catabolic but can function as anabolic

Question 5

2 phases of the PPP

Answer 5

oxidative
non-oxidative

Question 6

what is glutathione

Answer 6

tripeptide made of glutamate, cysteine, and glycine

Question 7

what is the precursor for serine?

Answer 7

3-phosphoglycerate

Question 8

catecholamines made from tyrosine

Answer 8

dopamine, norepinephrine, epinephrine

Question 9

what does amino acid biosynthesis require as a cofactor for transamination, tetrahydrofolate and S-adenosyl methionine?

Answer 9

pyridoxal phosphate

Question 10

what 3 allosteric mechanisms regulate amino acid biosynthesis?

Answer 10

feedback inhibition, concerted inhibition, and enzyme multiplicity