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Pedia > Pedia Oncology > Flashcards

Pedia Oncology Flashcards

1
Q

Most common malignant neoplasm in childhood

A

ALL

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2
Q

Peak incidence of ALL & gender predominance

A

2-6yrs old

M>F

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3
Q

Diagnostic test for ALL

A

Bone marrow aspiration with PBS:

Anemia, thrombocytopenia, median wbc: 33,000, lymphoblasts in the BM and PBS

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4
Q

Sites of relapse of ALL

A

Bone marrow
CNS
Testes

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5
Q

Poor prognostic factors for ALL

A 
Male
WBC >100,000 u/L on presentation
presence of CNS leukemia
Presence of mediastinal mass
Less than 2 or more than 10yrs old
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6
Q

Variant of Hodgkin’s lymphoma with the best prognosis

A

Lymphocyte-predominant

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7
Q

EBV is associated with what type subtype of NHL?

A

Burkitt’s lymphoma

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8
Q

Most common solid tumors in childhood?

A

Brain tumors

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9
Q

Most common posterior fossa tumor of childhood; has the best prognosis

A

Cerebellar Astrocytoma

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10
Q

Very aggressive post fossa tumor which can metastasize to extracranial sites

A

Medulloblastoma

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11
Q

Presents with painless flank mass that does not cross the midline

A

Wilm’s Tumor

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12
Q

Wilm’s tumor with worse prognosis

A

Large tumor >500gms
St III-IV
Unfavorable histologic types (anaplastic)

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13
Q

Presents with non-tender abdominal mass which may cross the midline

A

Neuroblastoma

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14
Q

Treatment for INSS stage 4s

A

Observation (nearly 100% survival)

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15
Q

Most common histologic type of Rhabdomyosarcoma?

A

Embryonal

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16
Q

Histologic type of Rhabdomyosarcoma with the worst prognosis

A

Alveolar

17
Q

Classic x-Ray finding: Sunburst pattern

A

Osteosarcoma

18
Q

X-ray: onion-skinning (“moth eaten” appearance)

A

Ewing sarcoma

19
Q

Complication of treatment of ALL

A

Tumor lysis syndrome

20
Q

Tumor lysis syndrome presents with

A

Hyperkalemia
Hyperphostatemia
Hyperuricemia
Hypocalcemia

21
Q

Reed-Sternberg cell

A

Hodgkin’s Lymphoma

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