PE

Question 1

wells score for PE

Answer 1

Clinical signs and symptoms of DVT

No0
Yes+3

PE is #1 diagnosis OR equally likely

No0
Yes+3

Heart rate > 100
No0
Yes+1.5

Immobilization at least 3 days OR surgery in the previous 4 weeks

No0
Yes+1.5

Previous, objectively diagnosed PE or DVT

Hemoptysis

4 or less PE unlikely

Question 2

Differentials for SOB?

Answer 2

Pneumothorax

If young- pulmonary hypertension

Infection

Cardiomyopathy in young

Pericarditis / myocarditis

Question 3

Pulmonary hypertension dx and treatment

Answer 3

administration of vasodilators such as intravenous epoprostenol or inhaled nitric oxide.
Or in patient Echo

If there is a positive response to acute vasodilator testing (a minority of patients)
oral calcium channel blockers

If there is a negative response to acute vasodilator testing (the vast majority of patients)
prostacyclin analogues: treprostinil, iloprost
endothelin receptor antagonists: bosentan, ambrisentan
phosphodiesterase inhibitors: sildenafil