PDD 01: Module Introduction Flashcards
What are the best dosage forms for systemic use?
- oral – tablet/capsule
- rectal – tablet/capsule
- IV
- IM
- transdermal patch
What are the best dosage forms for local use?
- transdermal patch
- topical cream/lotion
- eye drops
- ear drops
What are some therapeutic considerations for dosage forms for emergency use?
- rapid onset
- unconscious patient
What are the best dosage forms for emergency use?
- IV
- IM
- sublingual
- inhalation
What are some therapeutic considerations for dosage forms for young children?
- liquid
- taste
- user-friendly device
What are some therapeutic considerations for dosage forms for elderly?
- liquid
- user-friendly device
- uncomplicated dosing
- sustained-release dosage form
What are excipients?
pharmaceutical ingredients in a dosage form other than the active agent
- have significant effects on efficacy of drug
What are some excipients that increase solubility? (2)
- solvents
- surfactants
What are some excipients that increase palatability? (1)
sweeteners
What are some excipients that increase stability? (2)
- antimicrobials
- antioxidants
What are some ‘other’ (ie. tablet) excipients? (4)
- diluents (fillers)
- binders
- lubricants
- disintegrating agents
What is the importance of diluents?
safe and convenient delivery of accurate dosage
What is the importance of solubilizers?
IV formulation
