PCSK9 inhibitors Flashcards

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1
Q

What is an example of PCSK9 inhibitor?

A

Alirocumab (monoclonal antibody)

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2
Q

What is the mechanism of action of alirocumab

A
  • PCSK9 inhibition
  • Increases reuptake of LDL by liver
  • Increases LDL clearance
  • Works in hepatocyte only!
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3
Q

What is the mode of administration of aluricumab?

A

Subcutaneous (injection)

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