PCSK9 inhibitors Flashcards
1
Q
What is an example of PCSK9 inhibitor?
A
Alirocumab (monoclonal antibody)
2
Q
What is the mechanism of action of alirocumab
A
- PCSK9 inhibition
- Increases reuptake of LDL by liver
- Increases LDL clearance
- Works in hepatocyte only!
3
Q
What is the mode of administration of aluricumab?
A
Subcutaneous (injection)