Path Mem Jogger Flashcards

1
Q

Nodes found in the DIP joint related to osteoarthritis are known as ______ nodes.

A

Heberden

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2
Q

Severe muscle destruction throughout the body is seen with WOTF?

A

Rhabdomyolysis

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3
Q

WOTF hormones most commonly play role in the pathogenesis of breast cancer?

A

Estrogen

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4
Q

Damage to WOTF nerves may result in winging of the scapula?

A

Long thoracic

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5
Q

Non-tropical sprue is assoc with an intolerance of WOTF?

A

Gluten

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6
Q

Acromegaly develops in which period of life?

A

Post pubertal

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7
Q

WOTF tissues displays liquefactive necrosis?

A

Brain tissue

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8
Q

WOTF would you see (what would result) if a patient was in a cast?

A

Disuse atrophy

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9
Q

Which cell response is the typical in response to chronic irritation of the bronchi?

A

Metaplasia

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10
Q

WOTF will result in secondary liver cancer?

A

Chronic hepatitis C

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11
Q

WOTF in excess will mimic brain cancer?

A

Vitamin A

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12
Q

What is the vector for Lyme disease?

A

Deer Ticks

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13
Q

WOTF conditions produces antibodies to Ach receptors?

A

Myasthenia Gravis

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14
Q

WOTF will cause Korsakoff syndrome?

A

Thiamine deficiency

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15
Q

Erythroblastosis Fetalis is what type of hypersensitivity reaction?

A

Type 2

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16
Q

Hypofunction of posterior pituitary could result in development of WOTF?.

A

Diabetes insipidus

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17
Q

A male with limited secondary sex char, tall with long legs and hypogonadism is WOTF?

A

Klinefelter

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18
Q

WOTF makes up Arnold Chiari malformation?

A

Herniation of the cerebellar tonsils thru the FM

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19
Q

Which type of hypersensitivity reaction contains histamine?

A

Type 1 (IgE)

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20
Q

WOTF disorders present monosodium urate crystals?

A

Gout

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21
Q

WOTF is not seen in the teratology of Fallot?

A

Artial septal defect

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22
Q

WOTF heart defects is only seen when you become an adult?

A

Artial septal defect

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23
Q

WOTF is the most common joint pathology?

A

OA

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24
Q

If a cell changes shape and size, WOTF is it?

A

Dysplasia

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25
Q

What is the cell response of the esophageal mucosa to chronic inflammation in Barrett
esophagus?

A

Metaplasia

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26
Q

In which area of the body do you see Morton’s neuroma?

A

Foot

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27
Q

In which area of the body do the prostate cancer metastases most commonly occur?

A

Spine

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28
Q

What tumor is commonly seen in the distal femur and proximal tibia area?

A

Giant cell tumor

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29
Q

Temporal arteritis is seen in the temporal, ophthalmic and ______ arteries?

A

Vertebral

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30
Q

WOTF disorders develops only in the colon?

A

Hirschprung dx

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31
Q

WOTF is the most common CNS tumor?

A

Astrocytoma

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32
Q

Bruton’s disease is a deficiency of WOTF?

A

B cells

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33
Q

Fat malabsorption could results in the deficiency of WOTF?

A

Vit D (also A, E, K)

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34
Q

Claw hand results from a lesion to which nerve?

A

Ulnar

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35
Q

WOTF is assoc with pheochromocytoma?

A

Hypertension

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36
Q

WOTF disorders is associated with development of esophageal stricture due to long-standing gastroesophageal reflux?

A

Barrett esophagus

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37
Q

Clotting factor VIII deficiency is seen in WOTF diseases?

A

Hemophilia A

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38
Q

If you have a hair tuft on the skin over the spine, what do you suspect?

A

Spina bifida

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39
Q

WOTF is characterized by lytic lesions in the skull, diabetes insipidus and exopthalamus?

A

Hand-Schuller-Christian Disease

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40
Q

In WOTF areas, is endometriosis most commonly seen?

A

Ovaries

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41
Q

What is the most common cause of UTI in women?

A

E. COLI

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42
Q

WOTF is a polyneuropathy of the PNS that has ascending paralysis?

A

Guillian-Barre

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43
Q

What is the cause of Down’s syndrome?

A

Translocation mutation

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44
Q

WOTF is an antigen presenting cell?

A

Macrophage

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45
Q

Where does IL1 come from?

A

Macrophage

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46
Q

WOTF is NOT involved in the antigen presenting cycle?

A

Neutrophil

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47
Q

WOTF are the secretory antibodies?

A

IgA

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48
Q

WOTF of the following cells originate from the megakaryocyte?

A

Platelets

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49
Q

The variable region of the ab binding site is responsible for?

A

Antigen binding site

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50
Q

Constant injury of an extremity is most likely to be accompanied by WOTF?

A

Myositis ossificans

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51
Q

What is the cause of pernicious anemia?

A

Vitamin B12 deficiency

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52
Q

If you have iron deficiency, WOTF would occur?

A

Microcytic, hypochromic anemia

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53
Q

WOTF pigments would you see in the cells of heart and liver in an elderly pt?

A

Lipofuscin granules

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54
Q

WOTF diseases is characterized by conjunctivitis, urethritis and arthritis?

A

Reiter’s syndrome

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55
Q

WOTF organs are involved in Goodpasture’s syndrome?

A

Lungs and kidneys

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56
Q

WOTF diseases could cause left ventricular failure?

A

Systemic hypertension

57
Q

Thrombocytopenia is seen with WOTF?

A

Aplastic anemia

58
Q

Myasthenia Gravis will primarily effect WOTF muscles?

A

Extraocular muscles

59
Q

Where is osteosarcoma most commonly seen?

A

Distal femur and proximal tibia

60
Q

WOTF is the cause of osteopetrosis?

A

Decreased osteoclastic activity

61
Q

Pulmonary embolism is most likely to originate in WOTF?

A

Lower limb thrombi

62
Q

If you have pancreatitis, what lab test do you perform?

A

Amylase

63
Q

What’s a hapten?

A

Partial antigen

64
Q

WOTF is involved in acute inflammation?

A

Leukotrienes

65
Q

WOTF is the most common predisposing factor for development of cervical cancer?

A

Human Papilloma virus

66
Q

An increase in blood pressure in the upper extremity and decrease in blood pressure in the lower extremity is seen in WOTF?

A

Coarctation of aorta

67
Q

Most common site of a berry aneurysm?

A

Circle of Willis

68
Q

WOTF is the most common area in the cranial fossas to find an aneurysm?

A

Subarachnoid space

69
Q

If a child has influenza and takes aspirin at the same time, WOTF conditions can occur?

A

Reye’s syndrome

70
Q

If a pt has a tumor of the pit gland, which sinus will be affected?

A

Sphenoid

71
Q

Antiglomerulus and antialveolar basement membrane antibodies develop in WOTF diseases?

A

Goodpasture’s syndrome

72
Q

Osteomalacia may be due to a malabsorption of?

A

Vit D

73
Q

WOTF inclusion bodies are characteristic of Parkinsons disease?

A

Lewy bodies

74
Q

Pernicious anemia is caused by WOTF vitamin deficiency?

A

B12

75
Q

WOTF receptors T-helper have?

A

CD4

76
Q

WOTF receptors T-suppresors have?

A

CD8

77
Q

Transection of a nerve leads to ______ degeneration?

A

Wallerian

78
Q

WOTF conditions cause atrophy of the villi with resultant malabsorption?

A

Celiac sprue

79
Q

WOTF is the most common neoplasm in the heart?

A

Myxoma

80
Q

Primary sign of atherosclerosis?

A

Fatty streak

81
Q

Acromegaly is caused by?

A

Growth Hormone pituitary adenoma

82
Q

Raynauds dx is characterized by?

A

Vasospasm of digit small vessels (white-blue-red)

83
Q

WOTF terms designates effusion in the abdominal cavity?

A

Ascites

84
Q

Histamine is produced by WOTF?

A

Mast cells (they also prod heparin)

85
Q

Opsonins promote WOTF?

A

Phagocytosis

86
Q

WOTF are the major microscopic abnormalities in Alzheimer disease?

A

Neurofibrillary tangles, senile plaques, amyloid angiopathy

87
Q

Which subpopulation of WBC is increased in parasitic infection?

A

Eosinophils

88
Q

WOTF conditions are characterized by the presence of a 45,X karyotype?

A

Turner syndrome

89
Q

Most important vitamin in wound healing?

A

Vit C

90
Q

A disorder that affects the myoneural junction?

A

Myasthenia gravis

91
Q

T-helper cells account for WOTF types of hypersensitivity reactions?

A

Type IV

92
Q

Mesenchymal benign tumor originatingof striated muscle?

A

RHabdomyoma

93
Q

WOTF lesions are seen in secondary syphilis?

A

Condylomata lata

94
Q

WOTF is pathognomonic of Parkinson dx?

A

Lewy bodies

95
Q

Patients with Alzheimer are deficient in?

A

Ach

96
Q

Most common cause of cirrhosis of the liver?

A

Chronic alcoholism

97
Q

Most common fungal infection in a patient with AIDS?

A

Pneumocystis carinii

98
Q

WOTF malignant tumors gives an onion skin appearance?

A

Ewings

99
Q

What is the most common protozoan infection in an immunocompromised pt?

A

Toxoplasmosis

100
Q

In WOTF stages of syphilis could you see gumma?

A

Tertiary sphalis

101
Q

Von Recklinghausen’s disease aka?

A

Neurofibromatosis

102
Q

Fatty streaks in an organ are associated with?

A

Atherosclerosis

103
Q

AS (Ankylosing spondylitis) is an __________ dx?

A

Autoimmune

104
Q

WOTF areas of body is primarily involved in Duchenes muscular dystrophy?

A

Pelvic girdle

105
Q

Decrease in vitamin B12 can result in WOTF forms of anemia?

A

Megaloblastic

106
Q

WOTF is the most common benign tumor found in the uterus?

A

Leiomyoma

107
Q

WOTF is most common clinical manifestation found in Kwashiorkor?

A

Edema

108
Q

Marasmus is caused by WOTF deficiencies?

A

Lack of calorie, also low protein intake

109
Q

Cell response characterized by change in size, shape and function of the cell but ability to return to norm?

A

Dysplasia

110
Q

Woolsorters dx is an infection in the?

A

Resp System

111
Q

Movement of WBC’s in response to a concentration gradient is due to WOTF?

A

Chemotaxis

112
Q

Localized edema from filariasis is caused by _________ obstruction?

A

Lymphatic

113
Q

WOTF arteries is involved in giant cell arteritis?

A

Temporal artery

114
Q

Telescoping of the intestine is known as?

A

Intussusception

115
Q

Casseous necrosis is indicative of WOTF?

A

TB

116
Q

n WOTF diseases the cavitation in the spinal cord develops?

A

Syringomyelia

117
Q

Most common cause of ascites?

A

Cirrhosis

118
Q

WOTF are assoc with flattening of the villi?

A

Malabsorption

119
Q

WOTF ways can you differentiate chronic inflammation from acute inflammation?

A

Presence of fibrosis

120
Q

WOTF is the most common kidney stone?

A

Ca+ oxalate

121
Q

Metastasis to brain is most commonly from?

A

Lung cancer

122
Q

Phagocytosis is WOTF types of immunity?

A

Innate immunity

123
Q

WOTF is an example of type I hypersensitivity reaction?

A

Bronchial asthma

124
Q

WOTF is responsible for vasodilatation in acute inflammation?

A

Mast cells

125
Q

WOTF is an example of type II (cytotoxic) hypersensitivity reactions?

A

Erythroblastosis Fetalis

126
Q

WOTF is responsible for chronic cor pulmonale?

A

Emphysema

127
Q

Most common adult leukemia?

A

CLL (chronic lymphocytic leukemia)

128
Q

What is the difference between exudate and transudate?

A

Presence of protein

129
Q

Which chromosome is associated with CML (chronic myelogenous leukemia)?

A

22 (Philadelphia chromosome)

130
Q

WOTF is most likely to cause marasmus?

A

Starvation

131
Q

WOTF hepatitis can you get, get rid of and not be a carrier?

A

Type A

132
Q

WOTF is Bence Jones protein characteristic of?

A

MM (multiple myeloma)

133
Q

WOTF can cause hepatocellular cancer?

A

Hep Type C

134
Q

WOTF is an incomplete virus?

A

Hep Type D

135
Q

Negri bodies are associated with?

A

Rabies

136
Q

WOTF is most common disease for rock quarry workers?

A

Silicosis

137
Q

WOTF is the most common benign tumor of the spine?

A

Hemangioma

138
Q

WOTF is the most common area for giant cell tumor?

A

Distal femur and proximal tibia