Path Buzzwords Flashcards
Gross: “dewdrop”/ “waxy” appearance of the heart
A/w amyloidosis
Labs: Congo red stain + polarized light –> apple green birefringence
A/w amyloid (pathognomonic)
transthyretin deposits
A/w familial/hereditary amyloidosis (ATTR)
Gross: “golden brown” or “bronze skin”
A/w Hemachromatosis
Labs: guaiac positive stool
A/w Hemachromatosis (bc of portal hypertension and hemorrhoids)
Gross: small, cirrhotic liver with reddish brown discoloration
A/w Hemachromatosis (not diagnostic)
Labs: positive Prussian blue stain (on gross tissue or histo slide)
A/w Hemachromatosis (diagnostic - specific for iron)
Histo: golden brown pigment w/in hepatocytes
A/w Hemachromatosis (not diagnostic)
Liver histo: Kupffer cells
A/w Hemachromatosis (modified macrophage)
Hx: dry cough
A/w sarcoidosis
Chest x-ray: bilateral hilar lymphadenopathy
A/w sarcoidosis
Histo: noncaseating/non-necrotizing granulomas
A/w sarcoidosis (pretty diagnostic)
Histo: multinucleated giant cells
A/w granulomas (sarcoidosis for this exam)
Histo: asteroid body
A/w sarcoidosis (looks like a star)
Histo: Schaumann body
A/w sarcoidosis