Path Buzzwords Flashcards

1
Q

Gross: “dewdrop”/ “waxy” appearance of the heart

A

A/w amyloidosis

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2
Q

Labs: Congo red stain + polarized light –> apple green birefringence

A

A/w amyloid (pathognomonic)

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3
Q

transthyretin deposits

A

A/w familial/hereditary amyloidosis (ATTR)

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4
Q

Gross: “golden brown” or “bronze skin”

A

A/w Hemachromatosis

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5
Q

Labs: guaiac positive stool

A

A/w Hemachromatosis (bc of portal hypertension and hemorrhoids)

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6
Q

Gross: small, cirrhotic liver with reddish brown discoloration

A

A/w Hemachromatosis (not diagnostic)

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7
Q

Labs: positive Prussian blue stain (on gross tissue or histo slide)

A

A/w Hemachromatosis (diagnostic - specific for iron)

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8
Q

Histo: golden brown pigment w/in hepatocytes

A

A/w Hemachromatosis (not diagnostic)

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9
Q

Liver histo: Kupffer cells

A

A/w Hemachromatosis (modified macrophage)

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10
Q

Hx: dry cough

A

A/w sarcoidosis

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11
Q

Chest x-ray: bilateral hilar lymphadenopathy

A

A/w sarcoidosis

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12
Q

Histo: noncaseating/non-necrotizing granulomas

A

A/w sarcoidosis (pretty diagnostic)

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13
Q

Histo: multinucleated giant cells

A

A/w granulomas (sarcoidosis for this exam)

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14
Q

Histo: asteroid body

A

A/w sarcoidosis (looks like a star)

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15
Q

Histo: Schaumann body

A

A/w sarcoidosis

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16
Q

Complications: arrythmias

A

A/w sarcoidosis

17
Q

Complications: vision problems

A

A/w sarcoidosis

18
Q

Blood smear: rouleax formation

A

A/w amyloidosis (multiple myeloma/waldenstrom macroglobinuria)