Passmed Knowledge Flashcards

1
Q

What antibiotic is absolutely contraindicated with methotrextate

A

Trimethoprim

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2
Q

What is simmonds triad and what i it used for

A
  1. Calf Squeeze test
  2. Angle of declination at rest.
  3. palpation

used for achilles tendon rupture

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3
Q

Criteria for XR for ankle fracture

A

Pain in malleolar zone PLUS

  • Inability to walk more than 4 steps
  • Tenderness/Bony tenderness over the distal fibula
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4
Q

Weber classification

A

A: Below the syndesmosis
B: Level of tibial plafond but can radiate to include it
C: Above the syndesmosis

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5
Q

What are the 6 A’s of Ankylosing Spondylitis

A
Apical fibrosis
Anterior uveitis
Aortic regurgitation
Achilles tendonitis
AV node block
Amyloidosis
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6
Q

What is CREST syndrome? Name the parts of it.

A

Subtype of limited systemic sclerosis

Calcinosis
Raynauds
Oesophogeal Dysmotility
Sclerodactyly
Telangiectasia
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7
Q

What is a Charcot Joint?

What demographic commonly seen in?

A

Damaged joint due to loss of sensation.

Diabetics

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8
Q

Initial management of Osteoporosis with Bisphossphonates doesnt work. What next?

A

Try another bisphosphonate

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9
Q

What MSK condition can ciprofloxacin cause?

A

Achilles Tendonitis

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10
Q

Squaring of the thumbs?

A

Osteoarthritis

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11
Q

What nerve is most likely to be damaged following THR

A

Sciatic

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12
Q

+ve straight leg test indicates damage to which nerve

A

Sciatic

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13
Q

Next Step in management after Physio + NSAIDS in ANK SPOND

how many different NSAIDS have to be prescribed before moving down?

A

Biological Therapy (Anti-TNF)

2

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14
Q

Stepwise Management of Reactive Arthritis?

A
NSAIDS
Intra-articular injections (If one large joint involved)
Oral Pred (For multi joint)
DMARD
Biologic Therapy ANti TNF
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15
Q

What is used in monitoring of disease activity in SLE

A

Complement (LOW)

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16
Q

What DMARD is safe for use in pregnancy?

A

Azathioprine and Hydroxycholoroquine

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17
Q

HLA B27 is +ve in what?

A

Enteropathic Arthritis

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18
Q

Findings in XR for ANK SPOND (3)

A

Sclerosis
Subchondral Erosions
Squaring of vertebral body

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19
Q

What Drugs causes drug induced lupus and what is the atibody for it

A

Isoniazide/Procainamide/Hydralazine/Phenytoin

Anti-Histone

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20
Q

Renal complications of Systemic Sclerosis and management

A

Hypertension and AKI

ACEI’s

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21
Q

What are syndesmophytes and what are they found in?

A

Thickening of the outer annulus fibrosus

ANK SPOND

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22
Q

Three main side effects of bisphosphonates

A

Oesophageal Issues
Osteonecrosis of the Jaw
Stress Fractures

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23
Q

Investigation for cauda equina?

A

MRI

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24
Q

What part of a long bone is most affected in children with osteomyelitis?

A

Metaphysis

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25
Q

Features of Lupus

A

MD SOAP BRAIN

  • Malar Rash
  • Discoid Rash
  • Serositis (Pericarditis/Pleuritis)
  • Oral ulcers
  • Arthritis
  • Photosensitivity
  • Blood disturbance (i.e. anaemia of chronic disease/thrombocytopaenia)
  • Renal
  • ANA+
  • Immunological investigations (dsDNA-ABs/cadiolipin-ABs)
  • Neurological (seizures)
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26
Q

What drug used for Gout can cause diorrhoea

A

Colchicine

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27
Q

initial management of open fractures

A

IV AB’s
Photograph wound
sterile gauze

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28
Q

suspicious bone pain in children initial inestigation

A

XR

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29
Q

What can azathioprine not be given with and why?

A

Allopurinol

Bone Marrow Suppression

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30
Q

What is +ve in UC

A

pANCA

31
Q

What Neurovasvular structure is most at risk in a scaphoid fracture?

A

Dorsal Carpal Arch of the Radial Artery

32
Q

Occult Hip Fracture Investigation?

A

CT

33
Q

Initial mamagenent of suspected scaphoid fracture before specialist review

A

Futuro splint

34
Q

1st Line Ix in compartment syndrome

A

Compartment pressure monitoring

35
Q

What blood test would contraindicate azathioprine and why

A

TPMT

metabolises the drug, deficiency = toxicity

36
Q

test for hypermobility and scores to confirm +ve

A

Beighton Score

5/9 in adults 6/9 children

37
Q

Management of Grade 1-2 ACj injury?

A

Sling and Rest

38
Q

Management of Grade 3-6 ACL injury

A

Surgical Intervention

39
Q

malignancy and raised CK?

A

Polymyositis

40
Q

Causes of Dupuytrens Contracture (5)

A
manual labour
phenytoin treatment
alcoholic liver disease
diabetes mellitus
trauma to the hand
41
Q

Most common malginant primary bone tumour in children

Typpical appearance on XR

A

Osteosarcoma

Codmans triangle with sunburst appearancw

42
Q

Risk Factors for Congenital Hip Dislocation (5)

A
Female gender
Breech presentation
Family history
Firstborn
Oligohydramnios
43
Q

cANCA +ve? Vasculitis

A

GPA

44
Q

pANCA +ve? Vasculitis

A

EGPA (churg strauss)
Microscopic PA
Goodpastures

45
Q

Marked Claw?

A

Ulnar nerve damage at the wrist

46
Q

Clawing that gets worse before getting better?

A

Ulnar nerve damage at the elbow

47
Q

1st line for OA

A

Paracetamol and TOPICAL nsaids

48
Q

Where can you find Heberdens and Bouchards Nodes?

A

Heberdens: DIP Joints
Bouchards: PIP Joints

49
Q

Sulfasalazine cannot be given with what kind of antibiotics

A

Sulfa’s (Co-trimxazole)

50
Q

Flare up of rheumatoid?

A

IM Methylpredinsolone

51
Q

Are chemo patients more likely to get gout or pesudogout

A

Gout

52
Q

Ix of choice in Mortons Neuroma

A

US

53
Q

Signs and Investigations for Dequervains Tenosynovitis

A

Pain on radial side of wrist
Tenderness over radial styloid
Painful abduction of thumb against resistance
Finkelsteins Test: Fist with thumb inside and move wrist down (should be painful)

54
Q

Management of Dequervains Tenosynovitis

A

Analgesia and Steroid Injection

55
Q

Signs of Iliotibial Band Syndrome and Management

A

Pain in runners above lateral joint line

Modify activity and iliotibila band stretches/Physio

56
Q

Chondromalacia Patellae Signs and Management

A

Pain on walking up and down stairs in teenage girls

Physiotherapy

57
Q

Osgood-Schlatter Disease Key sign and management

A

Pain/Swelling over tibial tubercle

Physiotherapy

58
Q

Septic Arthritis:

Most common organism

Most common in sexually active young adults

A

Staph A

Neisseria Gonorrhoeae

59
Q

Intramedullar Nail used for?

A

Femoral Shaft Frac

Reverse oblique or transverse NOF frac

60
Q

Dynamic Hip Screw?

A

Extracapsular NOF Frac

61
Q

Management of:

Intracapsular NOF #

Intracapsular with bad premorbid status

Undisplaced Intracapsular

A

Total Hip Replacement

Hemiarthroplasty

Internal Fixation

62
Q

Polyarteritis Nodosa is associated with what?

A

Hep B

63
Q

Symptoms and Signs of Still’s Disease (4)

A

Salmon Pink Rash
Raised Ferritin
Dinnertime Fever
Arthralgia

64
Q

Management of Stills Disease

A

NSAIDS for a week, then steroids if no help

Resistant: DMARDS

65
Q

Mx of septic arthritis

A

IV fluclox

IV clindamycin if allergic

66
Q

Name 5 drugs that can induce lupus

A
Procainamide
Hydralazine
Isoniazide
Minocycline
Phenytoin
67
Q

Sjogrens increases risk of what kind of malignancy

A

Lymphoma

68
Q

Fertility problems with sulfasazlazine?

A

Reduced Sperm Count

69
Q

Cutaneous manifestation of methotrexate?

A

Ulcers

70
Q

Most common cause of septic arthritis in sexually active young adults

A

Neissieriah gonnorhoea

71
Q

Pagets treatment

A

IV bisphosphonates

72
Q

Essential test for osteroporosis in a young man?

A

testosterone

73
Q

How is radial head subluxation managed

A

Passive supination of the elbow flexed at 90 degrees

74
Q

Hill sachs lesions are associated with what?

A

Anterior shoulder dislocation