Paramyxoviridae

Question 1

Paramyxoviridae families

Answer 1

1. Paramxovirinae

2. Pneumovirinae

Question 2

Four genera of Paramyxovirinae with examples

Answer 2

Respirovirus: Parainfluenza 1,3
Rubelavirus: Parainfluenza 2,4
Morbilliovirus: Measles
Henipavirus: Hendra and Nipah In animals

Question 3

Two genera of pneumovirinae

Answer 3

Pneumoviruses : Respiratory Syncitia Virus A,B

Metapneumoviruses

Question 4

Site of infection initiation

Answer 4

Respiratory tract

Question 5

Structure of virus

Answer 5

1. Enveloped viruses
2. One piece of single stranded negative sense RNA
3. Non-segmented
4. Fragile
5. Pleomorphic but no filamentous forms
6. Loosely packed nucleocaspid
7. Contains hemagglutinin glycoprotein
8. Parainfluenza and mumps have neuraminidase
9. Have F protein which allows membrane fusion activity during replication
10. Cell to cell fusion allows syncitial formation