Paper 3 : Schizophrenia Key Studies Flashcards
Cheniaux et al
Two psychiatrists
100 patients
DSM : 26 and 13
ICD : 13 and 24
Buckley et al
50% of SZ also have depression
Joseph
MZ 40.4% DZ 7.4%
Ripke et al
108 genetic variations for increased risk of SZ
Tienari et al
19000 adopted children from parents with SZ
Greater risk of getting SZ
6.7% compared to 2%
Thorneley et al
Chlorpromazine more effective treatment than placebos meta analysis of 55 studies (typical)
Meltzer et al
Clozapine 40% more effective than typical
Tarrier et al
Combination of CBT and drugs most effective 315 patients
Read et al
69% of women and 59% of men report history of abuse
Fromm Reichman
Schizophrenogenic mother
Bateson 72
Double bind communication
Stirling et al
Compared 30 SZ patients with 18 controls in cognitive tasks. SZ patients x2 slower (supports central control dysfunctions)
Allen et al
Found lower activity levels in superior temporal gyrus
Genain quadruplets
All suffered from SZ
Hester was hospitalised most of her life
Myra was able to go to work
Myra was treated more favourably by her parents
Goldman Rakic et al
Found low levels or activity in pre frontal cortex (thinking and decision making) for dopamine.
